The Mutually Mediated Chloride Intracellular Channel Protein 1 (CLIC1) Relationship between Malignant Cells and Tumor Blood Vessel Endothelium Exhibits a Significant Impact on Tumor Angiogenesis, Progression, and Metastasis in Clear Cell Renal Cell Carcinoma (ccRCC)

SIMPLE SUMMARY: Tumor cells interact with endothelial cells via chloride intracellular channel protein 1 (CLIC1) micro vesicles transfer, inducing endothelial cell proliferation, migration, and tube formation, according to in vitro studies. Furthermore, CLIC1-positive tumor cells appear to have a hi...

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Detalles Bibliográficos
Autores principales: Ferician, Adela Maria, Ferician, Ovidiu Catalin, Nesiu, Alexandru, Cosma, Andrei Alexandru, Caplar, Borislav Dusan, Melnic, Eugen, Cimpean, Anca Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740861/
https://www.ncbi.nlm.nih.gov/pubmed/36497464
http://dx.doi.org/10.3390/cancers14235981

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