The Enigmatic Nature of the TCR-pMHC Interaction: Implications for CAR-T and TCR-T Engineering

The interaction of the T-cell receptor (TCR) with a peptide in the major histocompatibility complex (pMHC) plays a central role in the adaptive immunity of higher chordates. Due to the high specificity and sensitivity of this process, the immune system quickly recognizes and efficiently responds to...

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Detalles Bibliográficos
Autores principales: Shevyrev, D. V., Tereshchenko, V. P., Sennikov, S. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740949/
https://www.ncbi.nlm.nih.gov/pubmed/36499057
http://dx.doi.org/10.3390/ijms232314728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740949/
https://www.ncbi.nlm.nih.gov/pubmed/36499057
http://dx.doi.org/10.3390/ijms232314728

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