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The Enigmatic Nature of the TCR-pMHC Interaction: Implications for CAR-T and TCR-T Engineering

The interaction of the T-cell receptor (TCR) with a peptide in the major histocompatibility complex (pMHC) plays a central role in the adaptive immunity of higher chordates. Due to the high specificity and sensitivity of this process, the immune system quickly recognizes and efficiently responds to...

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Detalles Bibliográficos
Autores principales:	Shevyrev, D. V., Tereshchenko, V. P., Sennikov, S. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9740949/ https://www.ncbi.nlm.nih.gov/pubmed/36499057 http://dx.doi.org/10.3390/ijms232314728

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