Boron Trifluoride Etherate Promoted Regioselective 3-Acylation of Indoles with Anhydrides

An efficient, high-yielding and scalable procedure for the regioselective 3-acylation of indoles with anhydrides promoted by boron trifluoride etherate under mild conditions was reported. This novel protocol provided a simple way to prepare 3-(benzofuran-2-yl) indole in three steps.

Detalles Bibliográficos
Autores principales: Zheng, Yunyun, Li, Jiuling, Wei, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741063/
https://www.ncbi.nlm.nih.gov/pubmed/36500373
http://dx.doi.org/10.3390/molecules27238281
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author Zheng, Yunyun
Li, Jiuling
Wei, Kai
author_facet Zheng, Yunyun
Li, Jiuling
Wei, Kai
author_sort Zheng, Yunyun
collection PubMed
description An efficient, high-yielding and scalable procedure for the regioselective 3-acylation of indoles with anhydrides promoted by boron trifluoride etherate under mild conditions was reported. This novel protocol provided a simple way to prepare 3-(benzofuran-2-yl) indole in three steps.
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spelling pubmed-97410632022-12-11 Boron Trifluoride Etherate Promoted Regioselective 3-Acylation of Indoles with Anhydrides Zheng, Yunyun Li, Jiuling Wei, Kai Molecules Article An efficient, high-yielding and scalable procedure for the regioselective 3-acylation of indoles with anhydrides promoted by boron trifluoride etherate under mild conditions was reported. This novel protocol provided a simple way to prepare 3-(benzofuran-2-yl) indole in three steps. MDPI 2022-11-28 /pmc/articles/PMC9741063/ /pubmed/36500373 http://dx.doi.org/10.3390/molecules27238281 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zheng, Yunyun
Li, Jiuling
Wei, Kai
Boron Trifluoride Etherate Promoted Regioselective 3-Acylation of Indoles with Anhydrides
title Boron Trifluoride Etherate Promoted Regioselective 3-Acylation of Indoles with Anhydrides
title_full Boron Trifluoride Etherate Promoted Regioselective 3-Acylation of Indoles with Anhydrides
title_fullStr Boron Trifluoride Etherate Promoted Regioselective 3-Acylation of Indoles with Anhydrides
title_full_unstemmed Boron Trifluoride Etherate Promoted Regioselective 3-Acylation of Indoles with Anhydrides
title_short Boron Trifluoride Etherate Promoted Regioselective 3-Acylation of Indoles with Anhydrides
title_sort boron trifluoride etherate promoted regioselective 3-acylation of indoles with anhydrides
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741063/
https://www.ncbi.nlm.nih.gov/pubmed/36500373
http://dx.doi.org/10.3390/molecules27238281
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AT lijiuling borontrifluorideetheratepromotedregioselective3acylationofindoleswithanhydrides
AT weikai borontrifluorideetheratepromotedregioselective3acylationofindoleswithanhydrides

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