Cargando…

Rnd3 Is a Crucial Mediator of the Invasive Phenotype of Glioblastoma Cells Downstream of Receptor Tyrosine Kinase Signalling

Enhanced invasiveness is one of the defining biological traits of glioblastoma cells, which exhibit an infiltrative nature that severely hinders surgical resection. Among the molecular lesions responsible for GBM aggressiveness, aberrant receptor tyrosine kinase (RTK) signalling is well-characterise...

Descripción completa

Detalles Bibliográficos
Autores principales:	Almarán, Beatriz, Ramis, Guillem, Fernández de Mattos, Silvia, Villalonga, Priam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741382/ https://www.ncbi.nlm.nih.gov/pubmed/36496976 http://dx.doi.org/10.3390/cells11233716

Ejemplares similares

EGFR Inhibition in Glioma Cells Modulates Rho Signaling to Inhibit Cell Motility and Invasion and Cooperates with Temozolomide to Reduce Cell Growth
por: Ramis, Guillem, et al.
Publicado: (2012)

Glioblastoma Embryonic-like Stem Cells Exhibit Immune-Evasive Phenotype
por: Sesé, Borja, et al.
Publicado: (2022)

RND3 promotes Snail 1 protein degradation and inhibits glioblastoma cell migration and invasion
por: Liu, Baohui, et al.
Publicado: (2016)

The role of RICTOR downstream of receptor tyrosine kinase in cancers
por: Jebali, Ahlem, et al.
Publicado: (2018)

The Role of Hypoxia and SRC Tyrosine Kinase in Glioblastoma Invasiveness and Radioresistance
por: Torrisi, Filippo, et al.
Publicado: (2020)

Retama monosperma n-hexane extract induces cell cycle arrest and extrinsic pathway-dependent apoptosis in Jurkat cells
por: Belayachi, Lamiae, et al.
Publicado: (2014)

INDUCTION OF CELL CYCLE ARREST AND APOPTOSIS BY ORMENIS ERIOLEPIS A MORROCAN ENDEMIC PLANT IN VARIOUS HUMAN CANCER CELL LINES
por: Belayachi, Lamiae, et al.
Publicado: (2017)

Editorial expression of concern: Retama monosperma n-hexane extract induces cell cycle arrest and extrinsic pathway-dependent apoptosis in jurkat cells
por: Belayachi, Lamiae, et al.
Publicado: (2022)

EBP1: A crucial growth regulator downstream of receptor kinases across kingdoms
por: Stegmann, Martin
Publicado: (2018)

Role of Receptor Tyrosine Kinases and Their Ligands in Glioblastoma
por: Carrasco-García, Estefanía, et al.
Publicado: (2014)

Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes
por: Hsueh, Robert C, et al.
Publicado: (2002)

Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation
por: Oinuma, Izumi, et al.
Publicado: (2012)

Bruton's Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae
por: Liu, Zhe, et al.
Publicado: (2022)

Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications
por: Quintanal-Villalonga, A., et al.
Publicado: (2016)

Deciphering the Role of RND Efflux Transporters in Burkholderia cenocepacia
por: Bazzini, Silvia, et al.
Publicado: (2011)

RND2 attenuates apoptosis and autophagy in glioblastoma cells by targeting the p38 MAPK signalling pathway
por: Xu, Yang, et al.
Publicado: (2020)

Evaluation of Tyrosine Kinase Inhibitor Combinations for Glioblastoma Therapy
por: Joshi, Avadhut D., et al.
Publicado: (2012)

Receptor Tyrosine Kinase Signaling and Targeting in Glioblastoma Multiforme
por: Tilak, Manali, et al.
Publicado: (2021)

RND1 regulates migration of human glioblastoma stem-like cells according to their anatomical localization and defines a prognostic signature in glioblastoma
por: Boyrie, Sabrina, et al.
Publicado: (2018)

Corrigendum to “Tyrosine Kinase Receptor Landscape in Lung Cancer: Therapeutical Implications”
por: Quintanal-Villalonga, A., et al.
Publicado: (2018)

The spleen tyrosine kinase (SYK): A crucial therapeutic target for diverse liver diseases
por: Zhao, Yaping, et al.
Publicado: (2022)

Rho family GTPase 1 (RND1), a novel regulator of p53, enhances ferroptosis in glioblastoma
por: Sun, Qian, et al.
Publicado: (2022)

Receptor tyrosine kinases and downstream pathways as druggable targets for cancer treatment: the current arsenal of inhibitors
por: Montor, Wagner Ricardo, et al.
Publicado: (2018)

Lamellipodin-RICTOR Signaling Mediates Glioblastoma Cell Invasion and Radiosensitivity Downstream of EGFR
por: Moritz, Stefanie, et al.
Publicado: (2021)

RND multidrug efflux pumps: what are they good for?
por: Alvarez-Ortega, Carolina, et al.
Publicado: (2013)

Structural basis of RND-type multidrug exporters
por: Yamaguchi, Akihito, et al.
Publicado: (2015)

Tripartite assembly of RND multidrug efflux pumps
por: Daury, Laetitia, et al.
Publicado: (2016)

An RND transporter in the monoterpene metabolism of Castellaniella defragrans
por: Puentes-Cala, Edinson, et al.
Publicado: (2018)

Tyrosine Kinase Inhibitors in Adult Glioblastoma: An (Un)Closed Chapter?
por: Aldaz, Paula, et al.
Publicado: (2021)

Distinct Phenotypic Differences Associated with Differential Amplification of Receptor Tyrosine Kinase Genes at 4q12 in Glioblastoma
por: Burford, Anna, et al.
Publicado: (2013)

Downregulation of RND3/RhoE in glioblastoma patients promotes tumorigenesis through augmentation of notch transcriptional complex activity
por: Liu, Baohui, et al.
Publicado: (2015)

Small GTPase RHOE/RND3, a new critical regulator of NF‐κB signalling in glioblastoma multiforme?
por: Sun, Qian, et al.
Publicado: (2019)

PI3Kβ downstream of GPCRs – crucial partners in oncogenesis
por: Dbouk, Hashem A., et al.
Publicado: (2012)

Role of RND Efflux Pumps in Drug Resistance of Cystic Fibrosis Pathogens
por: Scoffone, Viola Camilla, et al.
Publicado: (2021)

Allopregnanolone Promotes Migration and Invasion of Human Glioblastoma Cells through the Protein Tyrosine Kinase c-Src Activation
por: Zamora-Sánchez, Carmen J., et al.
Publicado: (2022)

Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer
por: Chang, Q, et al.
Publicado: (2008)

The downstream of tyrosine kinase 7 is reduced in lung cancer and is associated with poor survival of patients with lung cancer
por: Chen, Gang, et al.
Publicado: (2017)

The ins and outs of RND efflux pumps in Escherichia coli
por: Anes, João, et al.
Publicado: (2015)

Receptor tyrosine kinase targeting in glioblastoma: performance, limitations and future approaches
por: Alexandru, Oana, et al.
Publicado: (2020)

Tyrosine Kinase Inhibitors for Glioblastoma Multiforme: Challenges and Opportunities for Drug Delivery
por: Brar, Harpinder K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8oi44vb0018v98r98j6c1up995