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Development of p-Tau Differentiated Cell Model of Alzheimer’s Disease to Screen Novel Acetylcholinesterase Inhibitors

Alzheimer’s disease (AD) is characterized by an initial accumulation of amyloid plaques and neurofibrillary tangles, along with the depletion of cholinergic markers. The currently available therapies for AD do not present any disease-modifying effects, with the available in vitro platforms to study...

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Detalles Bibliográficos
Autores principales:	Uras, Giuseppe, Li, Xinuo, Manca, Alessia, Pantaleo, Antonella, Bo, Marco, Xu, Jinyi, Allen, Stephanie, Zhu, Zheying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741399/ https://www.ncbi.nlm.nih.gov/pubmed/36499118 http://dx.doi.org/10.3390/ijms232314794

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