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Identification and Validation of RELN Mutation as a Response Indicator for Immune Checkpoint Inhibitor Therapy in Melanoma and Non-Small Cell Lung Cancer
Remarkable clinical benefits in several advanced cancers are observed under the treatment of immune checkpoint inhibitor (ICI) agents. However, only a smaller proportion of patients respond to the treatments. Reelin (RELN) is frequently mutated in the cancer genome. In this study, the RELN mutation...
Autores principales: | Li, Zhenpeng, Wang, Xin, Yang, Yi, Shi, Fuyan, Zhang, Wenjing, Wang, Qinghua, Wang, Suzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741468/ https://www.ncbi.nlm.nih.gov/pubmed/36497098 http://dx.doi.org/10.3390/cells11233841 |
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