Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice

Mice bred in 2017 and entered into the C2017 cohort were tested for possible lifespan benefits of (R/S)‐1,3‐butanediol (BD), captopril (Capt), leucine (Leu), the Nrf2‐activating botanical mixture PB125, sulindac, syringaresinol, or the combination of rapamycin and acarbose started at 9 or 16 months...

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Detalles Bibliográficos
Autores principales: Strong, Randy, Miller, Richard A., Cheng, Catherine J., Nelson, James F., Gelfond, Jonathan, Allani, Shailaja Kesaraju, Diaz, Vivian, Dorigatti, Angela Olsen, Dorigatti, Jonathan, Fernandez, Elizabeth, Galecki, Andrzej, Ginsburg, Brett, Hamilton, Karyn L., Javors, Martin A., Kornfeld, Kerry, Kaeberlein, Matt, Kumar, Suja, Lombard, David B., Lopez‐Cruzan, Marisa, Miller, Benjamin F., Rabinovitch, Peter, Reifsnyder, Peter, Rosenthal, Nadia A., Bogue, Molly A., Salmon, Adam B., Suh, Yousin, Verdin, Eric, Weissbach, Herbert, Newman, John, Maccchiarini, Francesca, Harrison, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741502/
https://www.ncbi.nlm.nih.gov/pubmed/36179270
http://dx.doi.org/10.1111/acel.13724

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