SIAH proteins regulate the degradation and intra‐mitochondrial aggregation of PINK1: Implications for mitochondrial pathology in Parkinson's disease

Parkinson's disease (PD) is characterized by degeneration of neurons, particularly dopaminergic neurons in the substantia nigra. PD brains show accumulation of α‐synuclein in Lewy bodies and accumulation of dysfunctional mitochondria. However, the mechanisms leading to mitochondrial pathology i...

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Detalles Bibliográficos
Autores principales: Abd Elghani, Fatimah, Safory, Hazem, Hamza, Haya, Savyon, Mor, Farhoud, Malik, Toren‐Hershoviz, Michal, Vitic, Zagorka, Ebanks, Kirsten, Shani, Vered, Bisharat, Sleman, Shaulov, Lihi, Brodski, Claude, Song, Zhiyin, Bandopadhyay, Rina, Engelender, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741505/
https://www.ncbi.nlm.nih.gov/pubmed/36307912
http://dx.doi.org/10.1111/acel.13731

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