Cargando…

Astragaloside IV Alleviates Brain Injury Induced by Hypoxia via the Calpain-1 Signaling Pathway

Long-term hypoxia can induce oxidative stress and apoptosis in hippocampal neurons that can lead to brain injury diseases. Astragaloside IV (AS-IV) is widely used in the antiapoptotic therapy of brain injury diseases. However, its mechanism of action is still not fully understood. In this study, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Yan, Yu, Shengxue, Zhao, Fang, Liu, Yu, Wang, Yue, Fan, Siqi, Su, Yuhong, Lu, Meili, Wang, Hongxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741538/ https://www.ncbi.nlm.nih.gov/pubmed/36510594 http://dx.doi.org/10.1155/2022/6509981

Ejemplares similares

Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway
por: Zhao, Fang, et al.
Publicado: (2022)

Astragaloside IV attenuates inflammatory response mediated by NLRP‐3/calpain‐1 is involved in the development of pulmonary hypertension
por: Sun, Yang, et al.
Publicado: (2020)

Calcium Sensing Receptor-Related Pathway Contributes to Cardiac Injury and the Mechanism of Astragaloside IV on Cardioprotection
por: Lu, Meili, et al.
Publicado: (2018)

Astragaloside IV alleviates myocardial damage induced by type 2 diabetes via improving energy metabolism
por: Zhang, Zhen, et al.
Publicado: (2019)

Astragaloside IV Alleviates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats
por: Shao, Anwen, et al.
Publicado: (2014)

Astragaloside IV Alleviates Infarction Induced Cardiomyocyte Injury by Improving Mitochondrial Morphology and Function
por: Zhang, Wen, et al.
Publicado: (2022)

Astragaloside IV Protects against Isoproterenol-Induced Cardiac Hypertrophy by Regulating NF-κB/PGC-1α Signaling Mediated Energy Biosynthesis
por: Zhang, Suping, et al.
Publicado: (2015)

Ginsenoside Rg1 ameliorates chronic intermittent hypoxia-induced vascular endothelial dysfunction by suppressing the formation of mitochondrial reactive oxygen species through the calpain-1 pathway
por: Zhao, Fang, et al.
Publicado: (2023)

Astragaloside IV alleviates heart failure by modulating Nrf-2
por: Feng, Wenxiao, et al.
Publicado: (2022)

Calpain‐1 mediates vascular remodelling and fibrosis via HIF‐1α in hypoxia‐induced pulmonary hypertension
por: Deng, Haiyan, et al.
Publicado: (2022)

Astragaloside IV alleviates heart failure by regulating SUMO-specific protease 1
por: Liu, Juan, et al.
Publicado: (2021)

Astragaloside IV protects human cardiomyocytes from hypoxia/reoxygenation injury by regulating miR-101a
por: Wu, Yang, et al.
Publicado: (2020)

Astragaloside IV alleviates placental oxidative stress and inflammation in GDM mice
por: Zhou, Ling, et al.
Publicado: (2020)

Astragaloside IV alleviates the symptoms of experimental ulcerative colitis in vitro and in vivo
por: Wu, Suxiao, et al.
Publicado: (2019)

Astragaloside IV alleviates heart failure by promoting angiogenesis through the JAK-STAT3 pathway
por: Sui, Yan-Bo, et al.
Publicado: (2019)

[Corrigendum] Astragaloside IV alleviates heart failure by regulating SUMO‑specific protease 1
por: Liu, Juan, et al.
Publicado: (2023)

Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR
por: Leng, Bin, et al.
Publicado: (2019)

Astragaloside IV attenuates hypoxia-induced pulmonary vascular remodeling via the Notch signaling pathway
por: Yao, Jiamei, et al.
Publicado: (2021)

Astragaloside IV attenuates hypoxia-induced pulmonary vascular remodeling via the Notch signaling pathway
por: Yao, Jiamei, et al.
Publicado: (2022)

Effects of Astragaloside IV on heart failure in rats
por: Zhao, Zhuanyou, et al.
Publicado: (2009)

Astragaloside IV (AS-IV) alleviates the malignant biological behavior of hepatocellular carcinoma via Wnt/β-catenin signaling pathway
por: Jiang, ZhongYu, et al.
Publicado: (2019)

Astragaloside IV ameliorates renal injury in db/db mice
por: Sun, Huili, et al.
Publicado: (2016)

Astragaloside IV alleviates liver injury in type 2 diabetes due to promotion of AMPK/mTOR-mediated autophagy
por: Zhu, Yunfeng, et al.
Publicado: (2021)

Research Progress on the Ability of Astragaloside IV to Protect the Brain Against Ischemia-Reperfusion Injury
por: Kang, Xianhui, et al.
Publicado: (2021)

Astragaloside IV protects cardiomyocytes against hypoxia injury via HIF-1α and the JAK2/STAT3 pathway
por: Li, Bei, et al.
Publicado: (2021)

Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy
por: Luo, Li-Fei, et al.
Publicado: (2021)

Astragaloside IV improves angiogenesis under hypoxic conditions by enhancing hypoxia-inducible factor-1α SUMOylation
por: Wang, Baoshen, et al.
Publicado: (2021)

Astragaloside IV Alleviates Ammonia-Induced Apoptosis and Oxidative Stress in Bovine Mammary Epithelial Cells
por: Wang, Fengge, et al.
Publicado: (2019)

Astragaloside IV Regulates cGAS-STING Signaling Pathway to Alleviate Immunosuppression Caused by PRRSV Infection
por: Song, Ke, et al.
Publicado: (2023)

Pharmacological Effects of Astragaloside IV: A Review
por: Liang, Yutong, et al.
Publicado: (2023)

Astragaloside IV alleviates lung inflammation in Klebsiella pneumonia rats by suppressing TGF-β1/Smad pathway
por: Li, Lei, et al.
Publicado: (2023)

Anticancer effects and mechanisms of astragaloside-IV
por: Zhou, Liangxing, et al.
Publicado: (2022)

Astragaloside IV alleviates stroke-triggered early brain injury by modulating neuroinflammation and ferroptosis via the Nrf2/HO-1 signaling pathway
por: Zhang, Chunlei, et al.
Publicado: (2023)

Astragaloside IV improves lipid metabolism in obese mice by alleviation of leptin resistance and regulation of thermogenic network
por: Wu, Hui, et al.
Publicado: (2016)

Astragaloside IV Alleviates Liver Inflammation, Oxidative Stress and Apoptosis to Protect Against Experimental Non-Alcoholic Fatty Liver Disease
por: Liang, Xiao-yu, et al.
Publicado: (2021)

Astragalus polysaccharides and astragaloside IV alleviate inflammation in bovine mammary epithelial cells by regulating Wnt/β-catenin signaling pathway
por: Fan, Jiaqi, et al.
Publicado: (2022)

Astragaloside IV: An Effective Drug for the Treatment of Cardiovascular Diseases
por: Tan, Yu-Qing, et al.
Publicado: (2020)

The Molecular Basis of the Anti-Inflammatory Property of Astragaloside IV for the Treatment of Diabetes and Its Complications
por: Li, Lin, et al.
Publicado: (2023)

Astragaloside IV improves renal function and alleviates renal damage and inflammation in rats with chronic glomerulonephritis
por: ZHANG, Dong, et al.
Publicado: (2022)

Protective effect of Astragalus membranaceus and Astragaloside IV in sepsis-induced acute kidney injury
por: Tang, Jia-Long, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ij6g0o3er9qg34q7e08d133c37