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Endosonography-Guided Tissue Acquisition for Diagnosis of Squamous Carcinoma of the Pancreas: A Report of Three Cases

While approximately 85% of neoplasms are ductal pancreatic adenocarcinomas (DPA), adenosquamous pancreatic carcinoma (APC) is a rare subtype of pancreatic cancer that exhibits aggressive behavior and poor prognosis. The authors report three cases of primary APC diagnosed through endoscopic ultrasoun...

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Autores principales: Ardengh, José C, Micelli-Neto, Otavio, Kemp, Rafael, dos Santos, José Sebastião
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741549/
https://www.ncbi.nlm.nih.gov/pubmed/36514643
http://dx.doi.org/10.7759/cureus.31344
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author Ardengh, José C
Micelli-Neto, Otavio
Kemp, Rafael
dos Santos, José Sebastião
author_facet Ardengh, José C
Micelli-Neto, Otavio
Kemp, Rafael
dos Santos, José Sebastião
author_sort Ardengh, José C
collection PubMed
description While approximately 85% of neoplasms are ductal pancreatic adenocarcinomas (DPA), adenosquamous pancreatic carcinoma (APC) is a rare subtype of pancreatic cancer that exhibits aggressive behavior and poor prognosis. The authors report three cases of primary APC diagnosed through endoscopic ultrasound-guided tissue acquisition (EUS-TA) using the new ProCore 20G needle, which had been developed to improve fine-needle aspiration results by providing more tissue for histopathology. Given its ability for microcore retrieval, pancreatic stroma examination, and excellent histopathology results, EUS-TA has exhibited exceptional diagnostic yield among patients with solid pancreatic lesions. All three APC cases presented herein had been accurately diagnosed using immunohistochemistry after microcore acquisition.
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spelling pubmed-97415492022-12-12 Endosonography-Guided Tissue Acquisition for Diagnosis of Squamous Carcinoma of the Pancreas: A Report of Three Cases Ardengh, José C Micelli-Neto, Otavio Kemp, Rafael dos Santos, José Sebastião Cureus Pathology While approximately 85% of neoplasms are ductal pancreatic adenocarcinomas (DPA), adenosquamous pancreatic carcinoma (APC) is a rare subtype of pancreatic cancer that exhibits aggressive behavior and poor prognosis. The authors report three cases of primary APC diagnosed through endoscopic ultrasound-guided tissue acquisition (EUS-TA) using the new ProCore 20G needle, which had been developed to improve fine-needle aspiration results by providing more tissue for histopathology. Given its ability for microcore retrieval, pancreatic stroma examination, and excellent histopathology results, EUS-TA has exhibited exceptional diagnostic yield among patients with solid pancreatic lesions. All three APC cases presented herein had been accurately diagnosed using immunohistochemistry after microcore acquisition. Cureus 2022-11-10 /pmc/articles/PMC9741549/ /pubmed/36514643 http://dx.doi.org/10.7759/cureus.31344 Text en Copyright © 2022, Ardengh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Ardengh, José C
Micelli-Neto, Otavio
Kemp, Rafael
dos Santos, José Sebastião
Endosonography-Guided Tissue Acquisition for Diagnosis of Squamous Carcinoma of the Pancreas: A Report of Three Cases
title Endosonography-Guided Tissue Acquisition for Diagnosis of Squamous Carcinoma of the Pancreas: A Report of Three Cases
title_full Endosonography-Guided Tissue Acquisition for Diagnosis of Squamous Carcinoma of the Pancreas: A Report of Three Cases
title_fullStr Endosonography-Guided Tissue Acquisition for Diagnosis of Squamous Carcinoma of the Pancreas: A Report of Three Cases
title_full_unstemmed Endosonography-Guided Tissue Acquisition for Diagnosis of Squamous Carcinoma of the Pancreas: A Report of Three Cases
title_short Endosonography-Guided Tissue Acquisition for Diagnosis of Squamous Carcinoma of the Pancreas: A Report of Three Cases
title_sort endosonography-guided tissue acquisition for diagnosis of squamous carcinoma of the pancreas: a report of three cases
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741549/
https://www.ncbi.nlm.nih.gov/pubmed/36514643
http://dx.doi.org/10.7759/cureus.31344
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