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Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments

Eps15-homology domain containing proteins (EHDs) are eukaryotic, dynamin-related ATPases involved in cellular membrane trafficking. They oligomerize on membranes into filaments that induce membrane tubulation. While EHD crystal structures in open and closed conformations were previously reported, li...

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Detalles Bibliográficos
Autores principales: Melo, Arthur A., Sprink, Thiemo, Noel, Jeffrey K., Vázquez-Sarandeses, Elena, van Hoorn, Chris, Mohd, Saif, Loerke, Justus, Spahn, Christian M. T., Daumke, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741607/
https://www.ncbi.nlm.nih.gov/pubmed/36496453
http://dx.doi.org/10.1038/s41467-022-35164-x