Cargando…

Cryo-electron tomography reveals structural insights into the membrane remodeling mode of dynamin-like EHD filaments

Eps15-homology domain containing proteins (EHDs) are eukaryotic, dynamin-related ATPases involved in cellular membrane trafficking. They oligomerize on membranes into filaments that induce membrane tubulation. While EHD crystal structures in open and closed conformations were previously reported, li...

Descripción completa

Detalles Bibliográficos
Autores principales:	Melo, Arthur A., Sprink, Thiemo, Noel, Jeffrey K., Vázquez-Sarandeses, Elena, van Hoorn, Chris, Mohd, Saif, Loerke, Justus, Spahn, Christian M. T., Daumke, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741607/ https://www.ncbi.nlm.nih.gov/pubmed/36496453 http://dx.doi.org/10.1038/s41467-022-35164-x

Ejemplares similares

CryoEM structure of the super-constricted two-start dynamin 1 filament
por: Liu, Jiwei, et al.
Publicado: (2021)

Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association
por: Sprink, Thiemo, et al.
Publicado: (2016)

Streamlined structure determination by cryo-electron tomography and subtomogram averaging using TomoBEAR
por: Balyschew, Nikita, et al.
Publicado: (2023)

Cryo-EM of the dynamin polymer assembled on lipid membrane
por: Kong, Leopold, et al.
Publicado: (2018)

EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization
por: Morén, Björn, et al.
Publicado: (2012)

Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor
por: Ganichkin, Oleg M., et al.
Publicado: (2021)

Invited review: Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily
por: Daumke, Oliver, et al.
Publicado: (2016)

EHDS are serine phosphoproteins: EHD1 phosphorylation is enhanced by serum stimulation
por: Fichtman, Boris, et al.
Publicado: (2008)

EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake
por: Matthaeus, Claudia, et al.
Publicado: (2020)

Cargo and Dynamin Regulate Clathrin-Coated Pit Maturation
por: Loerke, Dinah, et al.
Publicado: (2009)

ATP-dependent membrane remodeling links EHD1 functions to endocytic recycling
por: Deo, Raunaq, et al.
Publicado: (2018)

eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization
por: Matthaeus, Claudia, et al.
Publicado: (2019)

Eps 15 Homology Domain (EHD)-1 Remodels Transverse Tubules in Skeletal Muscle
por: Demonbreun, Alexis R., et al.
Publicado: (2015)

The role of PHIRI in the EHDS2
por: Bernal-Delgado, E, et al.
Publicado: (2022)

Renal Thrombotic Microangiopathy in Mice with Combined Deletion of Endocytic Recycling Regulators EHD3 and EHD4
por: George, Manju, et al.
Publicado: (2011)

A Review on Electrohydrodynamic (EHD) Pump
por: Peng, Yanhong, et al.
Publicado: (2023)

Early steps in primary cilium assembly require EHD1- and EHD3-dependent ciliary vesicle formation
por: Lu, Quanlong, et al.
Publicado: (2015)

Differential requirements for the Eps15 homology domain proteins EHD4 and EHD2 in the regulation of mammalian ciliogenesis
por: Jones, Tyler, et al.
Publicado: (2022)

CryoEM reveals different coronin binding modes for ADP- and ADP-BeFx- actin filaments
por: Ge, Peng, et al.
Publicado: (2014)

Electrohydrodynamic (EHD) drying of the Chinese wolfberry fruits
por: Yang, Maosheng, et al.
Publicado: (2016)

Nanoparticle assembly enabled by EHD-printed monolayers
por: Porter, Benjamin Francis, et al.
Publicado: (2017)

Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution
por: Hilal, Tarek, et al.
Publicado: (2016)

Cryo-electron microscopy structure of the filamentous bacteriophage IKe
por: Xu, Jingwei, et al.
Publicado: (2019)

Unveiling the polarity of actin filaments by cryo-electron tomography
por: Martins, Bruno, et al.
Publicado: (2021)

Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites
por: Ji, Wei-ke, et al.
Publicado: (2015)

Functional Mapping of Human Dynamin-1-Like GTPase Domain Based on X-ray Structure Analyses
por: Wenger, Julia, et al.
Publicado: (2013)

Electrohydrodynamics in dusty and dirty plasmas: gravito-electrodynamics and EHD
por: Kikuchi, Hiroshi
Publicado: (2001)

EHDs meet the retromer: Complex regulation of retrograde transport
por: Zhang, Jing, et al.
Publicado: (2012)

The Dynamin 2 inhibitor Dynasore affects the actin filament distribution during mouse early embryo development
por: WANG, Qiao-Chu, et al.
Publicado: (2014)

Cryo-EM structures of τ filaments from human brain
por: Goedert, Michel
Publicado: (2021)

Electron cryo-microscopy reveals the structure of the archaeal thread filament
por: Gaines, Matthew C., et al.
Publicado: (2022)

CryoET shows cofilactin filaments inside the microtubule lumen
por: Santos, Camilla Ventura, et al.
Publicado: (2023)

CryoET shows cofilactin filaments inside the microtubule lumen
por: Ventura Santos, Camilla, et al.
Publicado: (2023)

EHD1 Functions in Endosomal Recycling and Confers Salt Tolerance
por: Bar, Maya, et al.
Publicado: (2013)

Structured Cyclic Peptides That Bind the EH Domain of EHD1
por: Kamens, Alissa J., et al.
Publicado: (2014)

SUMOylation of EHD3 Modulates Tubulation of the Endocytic Recycling Compartment
por: Cabasso, Or, et al.
Publicado: (2015)

Entamoeba histolytica EHD1 Is Involved in Mitosome-Endosome Contact
por: Santos, Herbert J., et al.
Publicado: (2022)

Super-resolution analysis of PACSIN2 and EHD2 at caveolae
por: Nishimura, Tamako, et al.
Publicado: (2022)

EHDS2 pilot infrastructure for the secondary use of health data
por: Bacry, E, et al.
Publicado: (2022)

Redundant and Distinct Functions for Dynamin-1 and Dynamin-2 Isoforms
por: Altschuler, Yoram, et al.
Publicado: (1998)

Cannot write session to /tmp/vufind_sessions/sess_qrgdpvs416gs7ip491qvffn7r0