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Sirt6 attenuates chondrocyte senescence and osteoarthritis progression

Sirt6 has been implicated as a key regulator in aging-related diseases, including osteoarthritis. However, its functional role and molecular mechanism in chondrocyte senescence and osteoarthritis pathophysiology remain largely undefined. Here we show that Sirt6 deficiency exaggerates chondrocyte sen...

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Detalles Bibliográficos
Autores principales:	Ji, Ming-liang, Jiang, Hua, Li, Zhuang, Geng, Rui, Hu, Jun Zheng, Lin, Yu Cheng, Lu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741608/ https://www.ncbi.nlm.nih.gov/pubmed/36496445 http://dx.doi.org/10.1038/s41467-022-35424-w

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