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Stage-specific and cell type-specific requirements of ikzf1 during haematopoietic differentiation in zebrafish
The zinc finger transcription factor Ikaros1 (Ikzf1) is required for lymphoid development in mammals. Four zinc fingers constitute its DNA binding domain and two zinc fingers are present in the C-terminal protein interaction module. We describe the phenotypes of zebrafish homozygous for two distinct...
Autores principales: | Hess, Isabell, Sagar, O´Meara, Connor, Grün, Dominic, Schorpp, Michael, Boehm, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741631/ https://www.ncbi.nlm.nih.gov/pubmed/36496511 http://dx.doi.org/10.1038/s41598-022-25978-6 |
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