Cargando…

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Mixed lineage kinase domain‐like pseudokinase (MLKL), a key terminal effector of necroptosis, also plays a role in intracellular vesicle trafficking that is critical for regulating liver inflammation and injury in alcohol‐associated liver disease (ALD). Although receptor interacting protein kinase 3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Xiaoqin, Fan, Xiude, McMullen, Megan R., Miyata, Tatsunori, Kim, Adam, Pathak, Vai, Wu, Jianguo, Day, Le Z., Hardesty, Josiah E., Welch, Nicole, Dasarathy, Jaividhya, Allende, Daniela S., McCullough, Arthur J., Jacobs, Jon M., Rotroff, Daniel M., Dasarathy, Srinivasan, Nagy, Laura E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Articles: Steatohepatitis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741663/ https://www.ncbi.nlm.nih.gov/pubmed/35689613 http://dx.doi.org/10.1002/hep.32612

Ejemplares similares

Differential role of MLKL in alcohol-associated and non–alcohol-associated fatty liver diseases in mice and humans
por: Miyata, Tatsunori, et al.
Publicado: (2021)

Differential role of MLKL in alcohol-associated and non–alcohol-associated fatty liver diseases in mice and humans
por: Miyata, Tatsunori, et al.
Publicado: (2022)

Altered anti-viral immune responses in monocytes in overweight heavy drinkers
por: Kim, Adam, et al.
Publicado: (2023)

Plasma Krebs Cycle Intermediates in Nonalcoholic Fatty Liver Disease
por: Sandlers, Yana, et al.
Publicado: (2020)

Mincle-GSDMD-mediated release of IL-1β small extracellular vesicles from hepatic macrophages in ethanol-induced liver injury
por: Zhang, Quanri, et al.
Publicado: (2023)

Effect of Acid Suppressants on the Risk of COVID-19: A Propensity Score-Matched Study Using UK Biobank
por: Fan, Xiude, et al.
Publicado: (2021)

Alcohol Consumption is Associated with Poor Prognosis in Obese Patients with COVID-19: a Mendelian Randomization Study using UK Biobank
por: Fan, Xiude, et al.
Publicado: (2020)

Alcohol Consumption Is Associated with Poor Prognosis in Obese Patients with COVID-19: A Mendelian Randomization Study Using UK Biobank
por: Fan, Xiude, et al.
Publicado: (2021)

Clinical spectrum of non-alcoholic fatty liver disease in diabetic and non-diabetic patients()
por: Goh, George Boon-Bee, et al.
Publicado: (2014)

Dysregulated meta-organismal metabolism of aromatic amino acids in alcohol-associated liver disease
por: Mrdjen, Marko, et al.
Publicado: (2023)

Peripheral blood mononuclear cell mitochondrial dysfunction in acute alcohol‐associated hepatitis
por: Bellar, Annette, et al.
Publicado: (2023)

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis
por: Yan, Tingting, et al.
Publicado: (2023)

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study
por: Ren, Zhewen, et al.
Publicado: (2023)

The global epidemiology of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH): a systematic review
por: Younossi, Zobair M., et al.
Publicado: (2023)

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism
por: Deprince, Audrey, et al.
Publicado: (2023)

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
por: Afonso, Marta B., et al.
Publicado: (2023)

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis
por: Crespo, María, et al.
Publicado: (2023)

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice
por: Kim, Kyung Eun, et al.
Publicado: (2023)

Metabolic dysfunction‐associated fatty liver disease and excessive alcohol consumption are both independent risk factors for mortality
por: van Kleef, Laurens A., et al.
Publicado: (2023)

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
por: Juárez‐Fernández, María, et al.
Publicado: (2023)

The global fatty liver disease Sustainable Development Goal country score for 195 countries and territories
por: Lazarus, Jeffrey V., et al.
Publicado: (2023)

The outcome of boosting mitochondrial activity in alcohol-associated liver disease is organ-dependent
por: Goikoetxea-Usandizaga, Naroa, et al.
Publicado: (2023)

Tropifexor plus cenicriviroc combination versus monotherapy in nonalcoholic steatohepatitis: Results from the phase 2b TANDEM study
por: Anstee, Quentin M., et al.
Publicado: (2023)

Head-to-head comparison of magnetic resonance elastography-based liver stiffness, fat fraction, and T1 relaxation time in identifying at-risk NASH
por: Li, Jiahui, et al.
Publicado: (2023)

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness
por: Indira Chandran, Vineesh, et al.
Publicado: (2023)

Fatty liver disease is not associated with increased mortality in the elderly: A prospective cohort study
por: van Kleef, Laurens A., et al.
Publicado: (2023)

Hepatic mitochondrial NAD(+) transporter SLC25A47 activates AMPKα mediating lipid metabolism and tumorigenesis
por: Cheng, Lili, et al.
Publicado: (2023)

Association of non-alcoholic fatty liver disease and polycystic ovarian syndrome
por: Asfari, Mohammad Maysara, et al.
Publicado: (2020)

Hepatocellular carcinoma in nonalcoholic fatty liver disease with or without cirrhosis: a population-based study
por: Pinyopornpanish, Kanokwan, et al.
Publicado: (2021)

Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice
por: Helsley, Robert N, et al.
Publicado: (2022)

Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
por: Wu, Jianfeng, et al.
Publicado: (2013)

Consilience in sarcopenia of cirrhosis
por: Dasarathy, Srinivasan
Publicado: (2012)

Myostatin and beyond in cirrhosis: all roads lead to sarcopenia
por: Dasarathy, Srinivasan
Publicado: (2017)

Endogenous annexin A1 is a novel protective determinant in nonalcoholic steatohepatitis in mice
por: Locatelli, Irene, et al.
Publicado: (2014)

A Phase 1/2, Dose-Escalation Trial of Deferasirox for the Treatment of Iron Overload in HFE-Related Hereditary Hemochromatosis
por: Phatak, Pradyumna, et al.
Publicado: (2010)

A novel score of IL-13 and age predicts 90-day mortality in severe alcohol-associated hepatitis: A multicenter plasma biomarker analysis
por: Tornai, David, et al.
Publicado: (2023)

Identification of a MicroRNA‐E3 Ubiquitin Ligase Regulatory Network for Hepatocyte Death in Alcohol‐Associated Hepatitis
por: Fan, Xiude, et al.
Publicado: (2021)

The molecular mechanisms of MLKL-dependent and MLKL-independent necrosis
por: Li, Lu, et al.
Publicado: (2020)

Apolipoprotein CIII Overexpressing Mice Are Predisposed to Diet-Induced Hepatic Steatosis and Hepatic Insulin Resistance
por: Lee, Hui-Young, et al.
Publicado: (2011)

Dissociation Between APOC3 Variants, Hepatic Triglyceride Content and Insulin Resistance
por: Kozlitina, Julia, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_mhq0691vmlctqvgb611s9qd2ui