Cargando…

Blood Tests for Alzheimer’s Disease: Increasing Efforts to Expand and Diversify Research Participation Is Critical for Widespread Validation and Acceptance

The recent academic and commercial development, and regulatory approvals, of blood-based Alzheimer’s disease (AD) biomarkers are breakthrough developments of immense potential. However, clinical validation studies and therapeutic trial applications are limited almost exclusively to non-Hispanic Whit...

Descripción completa

Detalles Bibliográficos
Autor principal:	Karikari, Thomas K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Ethics Response
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741736/ https://www.ncbi.nlm.nih.gov/pubmed/35491788 http://dx.doi.org/10.3233/JAD-215730

Ejemplares similares

Strengthening Global Efforts to Combat Organ Trafficking and Transplant Tourism: Implications of the 2018 Edition of the Declaration of Istanbul
por: Martin, Dominique E., et al.
Publicado: (2019)

Reconsidering ‘minimal risk’ to expand the repertoire of trials with waiver of informed consent for research
por: Monach, Paul A, et al.
Publicado: (2021)

Self-directed multimedia process for delivering participant informed consent
por: Chapman, Niamh, et al.
Publicado: (2020)

2171: Satisfaction and perceptions of research participants in Clinical and Translational Studies
por: Otado, Jane A., et al.
Publicado: (2018)

Qualitative study of GPs’ views and experiences of population-based preconception expanded carrier screening in the Netherlands: bioethical perspectives
por: Morberg Jämterud, Sofia, et al.
Publicado: (2021)

Approaches to governance of participant-led research: a qualitative case study
por: Grant, Azure Dominique, et al.
Publicado: (2019)

Informal professionalization of healthy participants in phase I clinical trials in Russia
por: Zvonareva, Olga, et al.
Publicado: (2019)

The Alameda Model: An Effort Worth Emulating
por: Moulin, Aimee, et al.
Publicado: (2014)

What potential research participants want to know about research: a systematic review
por: Kirkby, Helen Michelle, et al.
Publicado: (2012)

Advance consent for participation in randomised controlled trials for emergency conditions: a scoping review
por: Niznick, Naomi, et al.
Publicado: (2023)

Public reporting of clinical trial findings as an ethical responsibility to participants: a qualitative study
por: Morrow, Richard L, et al.
Publicado: (2023)

Advanced consent for participation in acute care randomised control trials: protocol for a scoping review
por: Niznick, Naomi, et al.
Publicado: (2020)

Dissemination of trial results to participants in phase III pragmatic clinical trials: an audit of trial investigators intentions
por: Raza, M Zulfiqar, et al.
Publicado: (2020)

Cross-sectional assessment of patient attitudes towards participation in clinical trials: does making results publicly available matter?
por: Jones, Christopher W, et al.
Publicado: (2016)

Developing informed consent materials for non-English-speaking participants: An analysis of four professional firm translations from English to Spanish
por: Brelsford, Kathleen Marie, et al.
Publicado: (2018)

Money-oriented risk-takers or deliberate decision-makers: a cross-sectional survey study of participants in controlled human infection trials
por: Hoogerwerf, Marie-Astrid, et al.
Publicado: (2020)

Response to Moulin and Jones: “The Alameda Model: An Effort Worth Emulating”
por: Zeller, Scott
Publicado: (2014)

A critical appraisal of clinical trials conducted and subsequent drug approvals in India and South Africa
por: Limaye, Dnyanesh, et al.
Publicado: (2015)

Acceptability of donor funding for clinical trials in the UK: a qualitative empirical ethics study using focus groups to elicit the views of research patient public involvement group members, research ethics committee chairs and clinical researchers
por: Shearman, Kirstie, et al.
Publicado: (2022)

The Lived Experience Of Participants in an African RandomiseD trial (LEOPARD): protocol for an in-depth qualitative study within a multisite randomised controlled trial for HIV-associated cryptococcal meningitis
por: Lawrence, David S, et al.
Publicado: (2021)

Four reasons why too many informed consents to clinical research are invalid: a critical analysis of current practices
por: Wisgalla, Anne, et al.
Publicado: (2022)

An adapted instrument to assess informed consent comprehension among youth and parents in rural western Kenya: a validation study
por: Afolabi, Muhammed Olanrewaju, et al.
Publicado: (2018)

Recommendation‐making in the emergency department: A qualitative study of how Canadian emergency physicians guide treatment decisions about resuscitation in critically ill patients
por: Ajzenberg, Henry, et al.
Publicado: (2023)

Prospective registration trends, reasons for retrospective registration and mechanisms to increase prospective registration compliance: descriptive analysis and survey
por: Hunter, Kylie Elizabeth, et al.
Publicado: (2018)

Re-Expanding Opportunities for American Descendants of Slavery to Build a More Inclusive and Diverse Global Health Workforce
por: Okegbe, Tishina
Publicado: (2021)

In response to Ballantyne and Schaefer’s ‘Consent and the ethical duty to participate in health data research’
por: Hepgul, Nilay, et al.
Publicado: (2019)

Potential research participants support the return of raw sequence data
por: Middleton, Anna, et al.
Publicado: (2015)

Is it acceptable to contact an anonymous egg donor to facilitate diagnostic genetic testing for the donor-conceived child?
por: Horton, Rachel, et al.
Publicado: (2019)

Widespread intron retention diversifies most cancer transcriptomes
por: Dvinge, Heidi, et al.
Publicado: (2015)

Widespread intronic polyadenylation diversifies immune cell transcriptomes
por: Singh, Irtisha, et al.
Publicado: (2018)

In the Eye of the Storm: Bioethics in the Time of COVID-19
por: MacKenzie, C. Ronald, et al.
Publicado: (2020)

Ethical Issues in the Treatment of Late-Stage Alzheimer’s Disease
por: Watt, Andrew D., et al.
Publicado: (2019)

A rebuttal to Akabayashi and colleagues’ criticisms of the iPSC stock project
por: Fujita, Misao, et al.
Publicado: (2019)

Acceptability of offering financial incentives to achieve medication adherence in patients with severe mental illness: a focus group study
por: Priebe, Stefan, et al.
Publicado: (2010)

Yes, donor-recipient sex is associated with transfusion-related outcomes in critically ill patients
por: Alshalani, Abdulrahman, et al.
Publicado: (2022)

A valid question: Could hate speech condition bias in the brain?
por: Murrow, Gail B., et al.
Publicado: (2016)

“Eugenics talk” and the language of bioethics
por: Wilkinson, S
Publicado: (2008)

The Nuremberg Code–A critique
por: Ghooi, Ravindra B.
Publicado: (2011)

Ethical challenges in fetal surgery
por: Smajdor, Anna
Publicado: (2010)

Ethics committees in India: Facing the challenges!
por: Kadam, Rashmi, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_nlasril48dihuckm5tel5r11nc