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Immunosenescence and inflamm-ageing in COVID-19

The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people with cardiovascular disease have been proven. New findings shed light on the role of aging pathways on life span and health age. New therapies that focus on aging-related pathways may positively impact the treat...

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Autores principales: Zinatizadeh, Mohammad Reza, Zarandi, Peyman Kheirandish, Ghiasi, Mohsen, Kooshki, Hamid, Mohammadi, Mozafar, Amani, Jafar, Rezaei, Nima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741765/
https://www.ncbi.nlm.nih.gov/pubmed/36516928
http://dx.doi.org/10.1016/j.arr.2022.101818
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author Zinatizadeh, Mohammad Reza
Zarandi, Peyman Kheirandish
Ghiasi, Mohsen
Kooshki, Hamid
Mohammadi, Mozafar
Amani, Jafar
Rezaei, Nima
author_facet Zinatizadeh, Mohammad Reza
Zarandi, Peyman Kheirandish
Ghiasi, Mohsen
Kooshki, Hamid
Mohammadi, Mozafar
Amani, Jafar
Rezaei, Nima
author_sort Zinatizadeh, Mohammad Reza
collection PubMed
description The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people with cardiovascular disease have been proven. New findings shed light on the role of aging pathways on life span and health age. New therapies that focus on aging-related pathways may positively impact the treatment of this acute respiratory infection. Using new therapies that boost the level of the immune system can support the elderly with co-morbidities against the acute form of COVID-19. This article discusses the effect of the aging immune system against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the pathways affecting this severity of infection.
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spelling pubmed-97417652022-12-12 Immunosenescence and inflamm-ageing in COVID-19 Zinatizadeh, Mohammad Reza Zarandi, Peyman Kheirandish Ghiasi, Mohsen Kooshki, Hamid Mohammadi, Mozafar Amani, Jafar Rezaei, Nima Ageing Res Rev Review The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people with cardiovascular disease have been proven. New findings shed light on the role of aging pathways on life span and health age. New therapies that focus on aging-related pathways may positively impact the treatment of this acute respiratory infection. Using new therapies that boost the level of the immune system can support the elderly with co-morbidities against the acute form of COVID-19. This article discusses the effect of the aging immune system against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the pathways affecting this severity of infection. Elsevier B.V. 2023-02 2022-12-11 /pmc/articles/PMC9741765/ /pubmed/36516928 http://dx.doi.org/10.1016/j.arr.2022.101818 Text en © 2022 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Zinatizadeh, Mohammad Reza
Zarandi, Peyman Kheirandish
Ghiasi, Mohsen
Kooshki, Hamid
Mohammadi, Mozafar
Amani, Jafar
Rezaei, Nima
Immunosenescence and inflamm-ageing in COVID-19
title Immunosenescence and inflamm-ageing in COVID-19
title_full Immunosenescence and inflamm-ageing in COVID-19
title_fullStr Immunosenescence and inflamm-ageing in COVID-19
title_full_unstemmed Immunosenescence and inflamm-ageing in COVID-19
title_short Immunosenescence and inflamm-ageing in COVID-19
title_sort immunosenescence and inflamm-ageing in covid-19
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741765/
https://www.ncbi.nlm.nih.gov/pubmed/36516928
http://dx.doi.org/10.1016/j.arr.2022.101818
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