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A comparison of different methods for the first-in-pediatric dose selection
BACKGROUND AND AIM: To conduct a pediatric clinical trial, it is important to optimize pediatric dose as accurately as possible. This is mainly because due to ethical reasons, children cannot be given several doses to evaluate pharmacokinetics, safety, and efficacy of a drug. METHODS: In this study,...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Whioce Publishing Pte. Ltd.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741938/ https://www.ncbi.nlm.nih.gov/pubmed/36518546 |