Cargando…

DIAPH3 is a prognostic biomarker and inhibit colorectal cancer progression through maintaining EGFR degradation

BACKGROUND: Actin cytoskeleton is connected with the processes of cell proliferation and migration in colorectal cancer (CRC). However, it is unknown how to accomplish these adjustments in CRC by actin cytoskeleton genes (ACGs) and here we investigated the role of hub prognosis‐related ACGs‐Diaphano...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Renli, Wu, Cheng, Wen, Jialing, Yu, Jianyang, Zhu, Huidong, Yu, Jinlong, Zou, Zhaowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9741984/ https://www.ncbi.nlm.nih.gov/pubmed/35538918 http://dx.doi.org/10.1002/cam4.4793

Ejemplares similares

Nonredundant roles of DIAPHs in primary ciliogenesis
por: Palander, Oliva, et al.
Publicado: (2021)

DIAPH1 mediates progression of atherosclerosis and regulates hepatic lipid metabolism in mice
por: Senatus, Laura, et al.
Publicado: (2023)

The pan-cancer analysis identified DIAPH3 as a diagnostic biomarker of clinical cancer
por: Chen, Xiaowei, et al.
Publicado: (2023)

Association of DIAPH1 gene polymorphisms with ischemic stroke
por: Ren, Zhanyun, et al.
Publicado: (2020)

Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase
por: Nishimura, Koutarou, et al.
Publicado: (2019)

DIAPH1 Promotes Laryngeal Squamous Cell Carcinoma Progression Through Cell Cycle Regulation
por: Yang, Jiechao, et al.
Publicado: (2021)

DIAPH3 governs the cellular transition to the amoeboid tumour phenotype
por: Hager, Martin H, et al.
Publicado: (2012)

Small Molecule Inhibition of Ligand-Stimulated RAGE-DIAPH1 Signal Transduction
por: Manigrasso, Michaele B., et al.
Publicado: (2016)

The RAGE/DIAPH1 Signaling Axis & Implications for the Pathogenesis of Diabetic Complications
por: Ramasamy, Ravichandran, et al.
Publicado: (2022)

Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity
por: Theophall, Gregory G., et al.
Publicado: (2023)

DIAPH3 promotes pancreatic cancer progression by activating selenoprotein TrxR1‐mediated antioxidant effects
por: Rong, Yefei, et al.
Publicado: (2020)

The Formin, DIAPH1, is a Key Modulator of Myocardial Ischemia/Reperfusion Injury
por: O'Shea, Karen M., et al.
Publicado: (2017)

Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors
por: Damiani, Devid, et al.
Publicado: (2016)

DIAPH2, PTPRD and HIC1 Gene Polymorphisms and Laryngeal Cancer Risk
por: Śnit, Mirosław, et al.
Publicado: (2021)

Association between DIAPH1 variant and posterior circulation involvement with Moyamoya disease
por: He, Shihao, et al.
Publicado: (2023)

Heterochirality results from reduction of maternal diaph expression in a terrestrial pulmonate snail
por: Noda, Takeshi, et al.
Publicado: (2019)

DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction
por: Lau, Eva On-Chai, et al.
Publicado: (2021)

Protein diaphanous homolog 1 (Diaph1) promotes myofibroblastic activation of hepatic stellate cells by regulating Rab5a activity and TGFβ receptor endocytosis
por: Liu, Donglian, et al.
Publicado: (2020)

Regulation of microtubule dynamics by DIAPH3 influences amoeboid tumor cell mechanics and sensitivity to taxanes
por: Morley, Samantha, et al.
Publicado: (2015)

The formin Drosophila homologue of Diaphanous2 (Diaph2) controls microtubule dynamics in colorectal cancer cells independent of its FH2-domain
por: Grueb, Saskia S., et al.
Publicado: (2019)

Knockdown of DIAPH3 Inhibits the Proliferation of Cervical Cancer Cells through Inactivating mTOR Signaling Pathway
por: Wan, Linling, et al.
Publicado: (2021)

DIAPH1 Is Upregulated and Inhibits Cell Apoptosis through ATR/p53/Caspase-3 Signaling Pathway in Laryngeal Squamous Cell Carcinoma
por: Yang, Jiechao, et al.
Publicado: (2019)

Transcriptomics and Metabolomics Identify Drug Resistance of Dormant Cell in Colorectal Cancer
por: Xie, Lang, et al.
Publicado: (2022)

Cx43 Inhibition Attenuates Sepsis-Induced Intestinal Injury via Downregulating ROS Transfer and the Activation of the JNK1/Sirt1/FoxO3a Signaling Pathway
por: Zou, Zhaowei, et al.
Publicado: (2019)

EGFR enhances the stemness and progression of oral cancer through inhibiting autophagic degradation of SOX2
por: Lv, Xiao‐Xi, et al.
Publicado: (2019)

S645C Point Mutation Suppresses Degradation of EGFR to Promote Progression of Glioblastoma
por: Huang, Wenda, et al.
Publicado: (2022)

BMP3 suppresses colon tumorigenesis via ActRIIB/SMAD2-dependent and TAK1/JNK signaling pathways
por: Wen, Jialing, et al.
Publicado: (2019)

Identification of Tumorigenic and Prognostic Biomarkers in Colorectal Cancer Based on microRNA Expression Profiles
por: Shi, Yuntao, et al.
Publicado: (2020)

Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with eosinophilia
por: Jawhar, Mohamad, et al.
Publicado: (2017)

DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress
por: Yepuri, Gautham, et al.
Publicado: (2023)

In-depth genetic and molecular characterization of diaphanous related formin 2 (DIAPH2) and its role in the inner ear
por: Chiereghin, Chiara, et al.
Publicado: (2023)

JMJD5 inhibits lung cancer progression by facilitating EGFR proteasomal degradation
por: Shen, Jing, et al.
Publicado: (2023)

EZH2 expression is a prognostic biomarker in patients with colorectal cancer treated with anti-EGFR therapeutics
por: Yamamoto, Itaru, et al.
Publicado: (2017)

Constitutive activation of DIA1 (DIAPH1) via C‐terminal truncation causes human sensorineural hearing loss
por: Ueyama, Takehiko, et al.
Publicado: (2016)

Homozygous Autosomal Recessive DIAPH1 Mutation Associated with Central Nervous System Involvement and Aspergillosis: A Rare Case
por: Esmaeilzadeh, Hossein, et al.
Publicado: (2022)

Hydroxygenkwanin Suppresses Non-Small Cell Lung Cancer Progression by Enhancing EGFR Degradation
por: Leu, Yann-Lii, et al.
Publicado: (2020)

Immediate Translation of Formin DIAPH1 mRNA after Its Exiting the Nucleus Is Required for Its Perinuclear Localization in Fibroblasts
por: Liao, Guoning, et al.
Publicado: (2013)

Drosophila homologue of Diaphanous 1 (DIAPH1) controls the metastatic potential of colon cancer cells by regulating microtubule-dependent adhesion
por: Lin, Yuan-Na, et al.
Publicado: (2015)

JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation
por: Zhang, Bo, et al.
Publicado: (2021)

HOXD8/DIAPH2-AS1 epigenetically regulates PAX3 and impairs HTR-8/SVneo cell function under hypoxia
por: Feng, Yaling, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ckfdn7n5pkkh60cvtpgnnq0sdg