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Hyperfunctioning parathyroid gland and skeletal involvement on [(18)F]fluorocholine PET/CT: one look with two views

Hyperparathyroidism is an endocrine disorder that may be associated with other metabolic diseases. Non-invasive imaging techniques including [(99m)Tc]Tc-sestamibi single-photon emission computed tomography (SPECT) and [(18)F]fluorocholine positron emission tomography (PET)/computed tomography (CT) p...

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Detalles Bibliográficos
Autores principales: Nappi, Carmela, Piscopo, Leandra, Klain, Michele, Mainolfi, Ciro Gabriele, Vergara, Emilia, Adamo, Daniela, Mignogna, Michele Davide, Cuocolo, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742067/
https://www.ncbi.nlm.nih.gov/pubmed/36504377
http://dx.doi.org/10.1186/s41824-022-00149-y
Descripción
Sumario:Hyperparathyroidism is an endocrine disorder that may be associated with other metabolic diseases. Non-invasive imaging techniques including [(99m)Tc]Tc-sestamibi single-photon emission computed tomography (SPECT) and [(18)F]fluorocholine positron emission tomography (PET)/computed tomography (CT) play a key role on management of patients with hyperparathyroidism. We report for the first time a case of a patient with evidence of both hyperfunctioning parathyroid tissue and multiple lytic bone lesions on [(18)F]fluorocholine PET/CT imaging. The present case report highlights the potential role of whole-body [(18)F]fluorocholine PET/CT for the identification of both parathyroid adenoma and multiple bone lesions in a single diagnostic setting.