Biomaterials‐based nanoparticles conjugated to regulatory T cells provide a modular system for localized delivery of pharmacotherapeutic agents

Type 1 diabetes (T1D) presents with two therapeutic challenges: the need to correct underlying autoimmunity and restore β‐cell mass. We harnessed the unique capacity of regulatory T cells (Tregs) and the T cell receptor (TCR) to direct tolerance induction along with tissue‐localized delivery of ther...

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Detalles Bibliográficos
Autores principales: Marshall, Gregory P., Cserny, Judit, Wang, Chun‐Wei, Looney, Benjamin, Posgai, Amanda L., Bacher, Rhonda, Keselowsky, Benjamin, Brusko, Todd M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742177/
https://www.ncbi.nlm.nih.gov/pubmed/36082558
http://dx.doi.org/10.1002/jbm.a.37442

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