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A phenomenological model of proton FLASH oxygen depletion effects depending on tissue vasculature and oxygen supply

INTRODUCTION: Radiation-induced oxygen depletion in tissue is assumed as a contributor to the FLASH sparing effects. In this study, we simulated the heterogeneous oxygen depletion in the tissue surrounding the vessels and calculated the proton FLASH effective-dose-modifying factor (FEDMF), which cou...

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Detalles Bibliográficos
Autores principales:	Zou, Wei, Kim, Haram, Diffenderfer, Eric S., Carlson, David J., Koch, Cameron J., Xiao, Ying, Teo, BoonKeng K., Kim, Michele M., Metz, James M., Fan, Yi, Maity, Amit, Koumenis, Costas, Busch, Theresa M., Wiersma, Rodney, Cengel, Keith A., Dong, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742361/ https://www.ncbi.nlm.nih.gov/pubmed/36518319 http://dx.doi.org/10.3389/fonc.2022.1004121

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