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The copper transporter CTR1 and cisplatin accumulation at the single-cell level by LA-ICP-TOFMS
More than a decade ago, studies on cellular cisplatin accumulation via active membrane transport established the role of the high affinity copper uptake protein 1 (CTR1) as a main uptake route besides passive diffusion. In this work, CTR1 expression, cisplatin accumulation and intracellular copper c...
Autores principales: | Schoeberl, Anna, Gutmann, Michael, Theiner, Sarah, Corte-Rodríguez, Mario, Braun, Gabriel, Vician, Petra, Berger, Walter, Koellensperger, Gunda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742377/ https://www.ncbi.nlm.nih.gov/pubmed/36518851 http://dx.doi.org/10.3389/fmolb.2022.1055356 |
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