Multicenter dose-escalation Phase I trial of mitomycin C pressurized intraperitoneal aerosolized chemotherapy in combination with systemic chemotherapy for appendiceal and colorectal peritoneal metastases: rationale and design

OBJECTIVES: Peritoneal metastasis (PM) from appendiceal cancer or colorectal cancer (CRC) has significant morbidity and limited survival. Pressurized intraperitoneal aerosolized chemotherapy (PIPAC) is a minimally invasive approach to treat PM. We aim to conduct a dose-escalation trial of mitomycin...

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Detalles Bibliográficos
Autores principales: Raoof, Mustafa, Sullivan, Kevin M., Frankel, Paul H., Fakih, Marwan, Synold, Timothy W., Lim, Dean, Woo, Yanghee, Paz, Isaac Benjamin, Fong, Yuman, Thomas, Rebecca Meera, Chang, Sue, Eng, Melissa, Tinsley, Raechelle, Whelan, Richard L., Deperalta, Danielle, Reymond, Marc A., Jones, Jeremy, Merchea, Amit, Dellinger, Thanh H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742457/
https://www.ncbi.nlm.nih.gov/pubmed/36560966
http://dx.doi.org/10.1515/pp-2022-0116

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