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Differential Neutralization of Apixaban, Betrixaban, Edoxaban, and Rivaroxaban by Andexanet Alfa as Measured by Whole Blood Thromboelastographic Analysis

INTRODUCTION: The available oral anti-Xa agents are routinely used for the management of thrombotic disorders. A molecularly modified recombinant coagulation FXa, also known as Andexanet Alfa (AA), that has been developed as an antidote to neutralize the bleeding effects of oral FXa inhibitors, such...

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Detalles Bibliográficos
Autores principales: Mehrotra, Siddharth, Hoppensteadt, Debra, Jeske, Walter, Siddiqui, Fakiha, Iqbal, Omer, Tafur, Alfonso, Lewis, Bruce, Jaradeh, Mark, Kantarcioglu, Bulent, Fareed, Jawed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742582/
https://www.ncbi.nlm.nih.gov/pubmed/36476125
http://dx.doi.org/10.1177/10760296221138297