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Hepatoprotective activity of andrographolide possibly through antioxidative defense mechanism in Sprague-Dawley rats

The aims of this study to assess the efficiency of AGL against acetaminophen (APAP)-induced hepatic toxicity that was generated by mitochondrial oxidative stress and glutathione depletion. Free radical scavenging potentiality was analyzed by using 2, 2-diphenyl-1-picrylhydrazyl (DPPH), hydrogen pero...

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Detalles Bibliográficos
Autores principales: Mondal, Milon, Sarkar, Chandan, Saha, Sushmita, Hossain, Md Naim, Norouzi, Roghayeh, Mubarak, Mohammad S., Siyadatpanah, Abolghasem, Wilairatana, Polrat, Hossain, Rajib, Islam, Muhammad Torequl, Coutinho, Henrique Douglas Melo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742837/
https://www.ncbi.nlm.nih.gov/pubmed/36518448
http://dx.doi.org/10.1016/j.toxrep.2022.04.007