Safety evaluation of dried L-tryptophan fermentation product in Sprague-Dawley rats

The subchronic toxicity of oral L-tryptophan produced by fermentation with metabolically engineered Corynebacterium glutamicum was evaluated in Sprague-Dawley rats. Doses of 0, 500, 1000, and 2000 mg/kg/day were administered to groups of 10 male and 10 female rats for 90 days. For the groups adminis...

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Detalles Bibliográficos
Autores principales: Ko, Soo Min, Park, Ji-Eun, Kim, Sang-Ho, Park, Myeong Kyu, Seol, Ja Kyung, Heo, In Kyung, Shin, Yong-Uk, Kim, So-Young, Kim, Yang Hee, Son, Woo-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742870/
https://www.ncbi.nlm.nih.gov/pubmed/36518375
http://dx.doi.org/10.1016/j.toxrep.2022.05.005

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