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In vitro evaluation of mutagenic, cytotoxic, genotoxic and oral irritation potential of nicotine pouch products

Non-clinical in vitro studies were conducted to investigate the characteristics of extracts from tobacco free nicotine pouches alongside a reference snus product and/or 1R6F reference cigarette. In vitro investigations were conducted in the Neutral Red Uptake (NRU) cytotoxicity assay, Bacterial Reve...

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Detalles Bibliográficos
Autores principales: Miller-Holt, Jacqueline, Baskerville-Abraham, Irene, Sakimura, Masanori, Fukushima, Toshiro, Puglisi, Andrea, Gafner, Jeremie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742906/
https://www.ncbi.nlm.nih.gov/pubmed/36518473
http://dx.doi.org/10.1016/j.toxrep.2022.06.008