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Phosphatase inhibition by sodium orthovanadate displays anti-inflammatory action by suppressing AKT-IKKβ signaling in RAW264.7 cells

Sodium orthovanadate (Na(3)VO(4)) is an inhibitor of phosphatases that acts as a phosphate analog and is being developed as an anti-diabetes drug. Phosphatases play important roles in inflammatory signal pathways by modulating the removal of phosphate moieties of key signaling proteins. However, the...

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Detalles Bibliográficos
Autores principales:	Kim, Han Gyung, Jeong, Seong-Gu, Kim, Ji Hye, Cho, Jae Youl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9742970/ https://www.ncbi.nlm.nih.gov/pubmed/36518371 http://dx.doi.org/10.1016/j.toxrep.2022.09.012

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