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Inactivation of the Mla system and outer-membrane phospholipase A results in disrupted outer-membrane lipid asymmetry and hypervesiculation in Bordetella pertussis

Bordetella pertussis is the causative agent of a respiratory infection known as whooping cough. With the goal of improving the production of outer-membrane vesicles (OMVs), we studied here the mechanisms that are involved in maintaining lipid asymmetry in the outer membrane of this organism. We iden...

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Detalles Bibliográficos
Autores principales: de Jonge, Eline F., Vogrinec, Lana, van Boxtel, Ria, Tommassen, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743053/
https://www.ncbi.nlm.nih.gov/pubmed/36518166
http://dx.doi.org/10.1016/j.crmicr.2022.100172