Ocular tropism of SARS-CoV-2 in animal models with retinal inflammation via neuronal invasion following intranasal inoculation

Although ocular manifestations are reported in patients with COVID-19, consensus on ocular tropism of SARS-CoV-2 is lacking. Here, we infect K18-hACE2 transgenic mice with SARS-CoV-2 using various routes. We observe ocular manifestation and retinal inflammation with production of pro-inflammatory cy...

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Detalles Bibliográficos
Autores principales: Jeong, Gi Uk, Kwon, Hyung-Jun, Ng, Wern Hann, Liu, Xiang, Moon, Hyun Woo, Yoon, Gun Young, Shin, Hye Jin, Lee, In-Chul, Ling, Zheng Lung, Spiteri, Alanna G., King, Nicholas J. C., Taylor, Adam, Chae, Ji Soo, Kim, Chonsaeng, Ahn, Dae-Gyun, Kim, Kyun-Do, Ryu, Young Bae, Kim, Seong-Jun, Mahalingam, Suresh, Kwon, Young-Chan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743116/
https://www.ncbi.nlm.nih.gov/pubmed/36509737
http://dx.doi.org/10.1038/s41467-022-35225-1

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