Serum Uromodulin Is a Possible Auxiliary Diagnostic Tool for Acute Tubular Injury and Acute Interstitial Nephritis: A Case Series

Recently, the usefulness of serum uromodulin (sUmod) as a novel renal biomarker has been attracting attention. Clinical evidence regarding sUmod measurements has been accumulated by analyzing cross-sectional data. However, little is known about the longitudinal data on sUmod. Therefore, we decided t...

Descripción completa

Detalles Bibliográficos
Autores principales: Usui, Ryosuke, Ogawa, Tetsuya, Iwasaki, Chihiro, Nitta, Kosaku, Koike, Minako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743145/
https://www.ncbi.nlm.nih.gov/pubmed/36518358
http://dx.doi.org/10.1159/000523855
_version_ 1784848670546460672
author Usui, Ryosuke
Ogawa, Tetsuya
Iwasaki, Chihiro
Nitta, Kosaku
Koike, Minako
author_facet Usui, Ryosuke
Ogawa, Tetsuya
Iwasaki, Chihiro
Nitta, Kosaku
Koike, Minako
author_sort Usui, Ryosuke
collection PubMed
description Recently, the usefulness of serum uromodulin (sUmod) as a novel renal biomarker has been attracting attention. Clinical evidence regarding sUmod measurements has been accumulated by analyzing cross-sectional data. However, little is known about the longitudinal data on sUmod. Therefore, we decided to investigate the variability of sUmod in patients with acute kidney injury due to different causes. High concentrations of sUmod have been observed in patients with acute tubular injury (ATI) and/or acute interstitial nephritis (AIN). sUmod could be used as an auxiliary diagnostic tool for ATI and AIN.
format Online
Article
Text
id pubmed-9743145
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher S. Karger AG
record_format MEDLINE/PubMed
spelling pubmed-97431452022-12-13 Serum Uromodulin Is a Possible Auxiliary Diagnostic Tool for Acute Tubular Injury and Acute Interstitial Nephritis: A Case Series Usui, Ryosuke Ogawa, Tetsuya Iwasaki, Chihiro Nitta, Kosaku Koike, Minako Case Rep Nephrol Dial Case Series Recently, the usefulness of serum uromodulin (sUmod) as a novel renal biomarker has been attracting attention. Clinical evidence regarding sUmod measurements has been accumulated by analyzing cross-sectional data. However, little is known about the longitudinal data on sUmod. Therefore, we decided to investigate the variability of sUmod in patients with acute kidney injury due to different causes. High concentrations of sUmod have been observed in patients with acute tubular injury (ATI) and/or acute interstitial nephritis (AIN). sUmod could be used as an auxiliary diagnostic tool for ATI and AIN. S. Karger AG 2022-10-11 /pmc/articles/PMC9743145/ /pubmed/36518358 http://dx.doi.org/10.1159/000523855 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Series
Usui, Ryosuke
Ogawa, Tetsuya
Iwasaki, Chihiro
Nitta, Kosaku
Koike, Minako
Serum Uromodulin Is a Possible Auxiliary Diagnostic Tool for Acute Tubular Injury and Acute Interstitial Nephritis: A Case Series
title Serum Uromodulin Is a Possible Auxiliary Diagnostic Tool for Acute Tubular Injury and Acute Interstitial Nephritis: A Case Series
title_full Serum Uromodulin Is a Possible Auxiliary Diagnostic Tool for Acute Tubular Injury and Acute Interstitial Nephritis: A Case Series
title_fullStr Serum Uromodulin Is a Possible Auxiliary Diagnostic Tool for Acute Tubular Injury and Acute Interstitial Nephritis: A Case Series
title_full_unstemmed Serum Uromodulin Is a Possible Auxiliary Diagnostic Tool for Acute Tubular Injury and Acute Interstitial Nephritis: A Case Series
title_short Serum Uromodulin Is a Possible Auxiliary Diagnostic Tool for Acute Tubular Injury and Acute Interstitial Nephritis: A Case Series
title_sort serum uromodulin is a possible auxiliary diagnostic tool for acute tubular injury and acute interstitial nephritis: a case series
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743145/
https://www.ncbi.nlm.nih.gov/pubmed/36518358
http://dx.doi.org/10.1159/000523855
work_keys_str_mv AT usuiryosuke serumuromodulinisapossibleauxiliarydiagnostictoolforacutetubularinjuryandacuteinterstitialnephritisacaseseries
AT ogawatetsuya serumuromodulinisapossibleauxiliarydiagnostictoolforacutetubularinjuryandacuteinterstitialnephritisacaseseries
AT iwasakichihiro serumuromodulinisapossibleauxiliarydiagnostictoolforacutetubularinjuryandacuteinterstitialnephritisacaseseries
AT nittakosaku serumuromodulinisapossibleauxiliarydiagnostictoolforacutetubularinjuryandacuteinterstitialnephritisacaseseries
AT koikeminako serumuromodulinisapossibleauxiliarydiagnostictoolforacutetubularinjuryandacuteinterstitialnephritisacaseseries

Ejemplares similares