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Triptolide promotes ferroptosis by suppressing Nrf2 to overcome leukemia cell resistance to doxorubicin

Doxorubicin (DOX) is an extensively used chemotherapeutic drug to treat leukemia. However, there remains a pivotal clinical problem of resistance to DOX in patients with leukemia. Erythroid 2-related factor 2 (Nrf2) is a master regulator of antioxidation response which serves a critical role in main...

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Detalles Bibliográficos
Autores principales:	Wu, Xia, Chen, Shangqing, Huang, Kechu, Lin, Gongping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743397/ https://www.ncbi.nlm.nih.gov/pubmed/36453238 http://dx.doi.org/10.3892/mmr.2022.12904

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