Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis)

INTRODUCTION: Sepsis is characterised by a dysregulated immune response to infection, with exaggerated pro-inflammatory and anti-inflammatory responses. A predominant immunosuppressive profile affecting both innate and adaptive immune responses is associated with increased hospital-acquired infectio...

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Detalles Bibliográficos
Autores principales: Scott, Jonathan, Trevi, Loredana, McNeil, Hannah, Ewen, Tom, Mawson, Phil, McDonald, David, Filby, Andrew, Lall, Ranjit, Booth, Katie, Boschman, Gert, Melkebeek, Vesna, Perkins, Gavin, McMullan, Ronan, McAuley, Daniel F, McCullagh, Iain J, Walsh, Timothy, Rostron, Anthony, Shankar-Hari, Manu, Dark, Paul, Simpson, A John, Conway Morris, Andrew, Hellyer, Thomas P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Intensive Care
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743405/
https://www.ncbi.nlm.nih.gov/pubmed/36600326
http://dx.doi.org/10.1136/bmjopen-2022-068321

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