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Granulation tissue-type hemangioma in a 6-week-old puppy – a case report
BACKGROUND: Hemangioma is a well-known neoplasia in veterinary and human medicine. Several subtypes have been described and are distinguished based on their histologic appearance. The classification schemes of hemangiomas in human and veterinary medicine are different, and various purpose-based sche...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743495/ https://www.ncbi.nlm.nih.gov/pubmed/36503485 http://dx.doi.org/10.1186/s12917-022-03503-1 |
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author | Müller, Janina Henrich, Manfred Hoogen-Merkel, Johanna Hartung, Svenja |
author_facet | Müller, Janina Henrich, Manfred Hoogen-Merkel, Johanna Hartung, Svenja |
author_sort | Müller, Janina |
collection | PubMed |
description | BACKGROUND: Hemangioma is a well-known neoplasia in veterinary and human medicine. Several subtypes have been described and are distinguished based on their histologic appearance. The classification schemes of hemangiomas in human and veterinary medicine are different, and various purpose-based schemes can be found in the literature. CASE PRESENTATION: A six-week-old puppy was presented that suffered from a neoplasia that extended to the musculature of the hind limb. After surgical excision, the mass was submitted for pathohistological examination. The mass was composed of endothelial cells forming vascular slits admixed with a fibrous stroma and spindle cells. Immunohistological examination was positive for factor VIII-related antigen and smooth muscle actin, supporting the diagnosis of hemangioma. CONCLUSION: The final diagnosis of granulation tissue-type hemangioma was given due to the histological appearance of the neoplasia. Granulation tissue-type hemangioma is a rare subtype of hemangioma. In this case an uncommonly young dog was affected. |
format | Online Article Text |
id | pubmed-9743495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-97434952022-12-13 Granulation tissue-type hemangioma in a 6-week-old puppy – a case report Müller, Janina Henrich, Manfred Hoogen-Merkel, Johanna Hartung, Svenja BMC Vet Res Case Report BACKGROUND: Hemangioma is a well-known neoplasia in veterinary and human medicine. Several subtypes have been described and are distinguished based on their histologic appearance. The classification schemes of hemangiomas in human and veterinary medicine are different, and various purpose-based schemes can be found in the literature. CASE PRESENTATION: A six-week-old puppy was presented that suffered from a neoplasia that extended to the musculature of the hind limb. After surgical excision, the mass was submitted for pathohistological examination. The mass was composed of endothelial cells forming vascular slits admixed with a fibrous stroma and spindle cells. Immunohistological examination was positive for factor VIII-related antigen and smooth muscle actin, supporting the diagnosis of hemangioma. CONCLUSION: The final diagnosis of granulation tissue-type hemangioma was given due to the histological appearance of the neoplasia. Granulation tissue-type hemangioma is a rare subtype of hemangioma. In this case an uncommonly young dog was affected. BioMed Central 2022-12-12 /pmc/articles/PMC9743495/ /pubmed/36503485 http://dx.doi.org/10.1186/s12917-022-03503-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Müller, Janina Henrich, Manfred Hoogen-Merkel, Johanna Hartung, Svenja Granulation tissue-type hemangioma in a 6-week-old puppy – a case report |
title | Granulation tissue-type hemangioma in a 6-week-old puppy – a case report |
title_full | Granulation tissue-type hemangioma in a 6-week-old puppy – a case report |
title_fullStr | Granulation tissue-type hemangioma in a 6-week-old puppy – a case report |
title_full_unstemmed | Granulation tissue-type hemangioma in a 6-week-old puppy – a case report |
title_short | Granulation tissue-type hemangioma in a 6-week-old puppy – a case report |
title_sort | granulation tissue-type hemangioma in a 6-week-old puppy – a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743495/ https://www.ncbi.nlm.nih.gov/pubmed/36503485 http://dx.doi.org/10.1186/s12917-022-03503-1 |
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