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Granulation tissue-type hemangioma in a 6-week-old puppy – a case report

BACKGROUND: Hemangioma is a well-known neoplasia in veterinary and human medicine. Several subtypes have been described and are distinguished based on their histologic appearance. The classification schemes of hemangiomas in human and veterinary medicine are different, and various purpose-based sche...

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Autores principales: Müller, Janina, Henrich, Manfred, Hoogen-Merkel, Johanna, Hartung, Svenja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743495/
https://www.ncbi.nlm.nih.gov/pubmed/36503485
http://dx.doi.org/10.1186/s12917-022-03503-1
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author Müller, Janina
Henrich, Manfred
Hoogen-Merkel, Johanna
Hartung, Svenja
author_facet Müller, Janina
Henrich, Manfred
Hoogen-Merkel, Johanna
Hartung, Svenja
author_sort Müller, Janina
collection PubMed
description BACKGROUND: Hemangioma is a well-known neoplasia in veterinary and human medicine. Several subtypes have been described and are distinguished based on their histologic appearance. The classification schemes of hemangiomas in human and veterinary medicine are different, and various purpose-based schemes can be found in the literature. CASE PRESENTATION: A six-week-old puppy was presented that suffered from a neoplasia that extended to the musculature of the hind limb. After surgical excision, the mass was submitted for pathohistological examination. The mass was composed of endothelial cells forming vascular slits admixed with a fibrous stroma and spindle cells. Immunohistological examination was positive for factor VIII-related antigen and smooth muscle actin, supporting the diagnosis of hemangioma. CONCLUSION: The final diagnosis of granulation tissue-type hemangioma was given due to the histological appearance of the neoplasia. Granulation tissue-type hemangioma is a rare subtype of hemangioma. In this case an uncommonly young dog was affected.
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spelling pubmed-97434952022-12-13 Granulation tissue-type hemangioma in a 6-week-old puppy – a case report Müller, Janina Henrich, Manfred Hoogen-Merkel, Johanna Hartung, Svenja BMC Vet Res Case Report BACKGROUND: Hemangioma is a well-known neoplasia in veterinary and human medicine. Several subtypes have been described and are distinguished based on their histologic appearance. The classification schemes of hemangiomas in human and veterinary medicine are different, and various purpose-based schemes can be found in the literature. CASE PRESENTATION: A six-week-old puppy was presented that suffered from a neoplasia that extended to the musculature of the hind limb. After surgical excision, the mass was submitted for pathohistological examination. The mass was composed of endothelial cells forming vascular slits admixed with a fibrous stroma and spindle cells. Immunohistological examination was positive for factor VIII-related antigen and smooth muscle actin, supporting the diagnosis of hemangioma. CONCLUSION: The final diagnosis of granulation tissue-type hemangioma was given due to the histological appearance of the neoplasia. Granulation tissue-type hemangioma is a rare subtype of hemangioma. In this case an uncommonly young dog was affected. BioMed Central 2022-12-12 /pmc/articles/PMC9743495/ /pubmed/36503485 http://dx.doi.org/10.1186/s12917-022-03503-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Müller, Janina
Henrich, Manfred
Hoogen-Merkel, Johanna
Hartung, Svenja
Granulation tissue-type hemangioma in a 6-week-old puppy – a case report
title Granulation tissue-type hemangioma in a 6-week-old puppy – a case report
title_full Granulation tissue-type hemangioma in a 6-week-old puppy – a case report
title_fullStr Granulation tissue-type hemangioma in a 6-week-old puppy – a case report
title_full_unstemmed Granulation tissue-type hemangioma in a 6-week-old puppy – a case report
title_short Granulation tissue-type hemangioma in a 6-week-old puppy – a case report
title_sort granulation tissue-type hemangioma in a 6-week-old puppy – a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743495/
https://www.ncbi.nlm.nih.gov/pubmed/36503485
http://dx.doi.org/10.1186/s12917-022-03503-1
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