Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling

BACKGROUND: Autoimmune disorders, including Systemic Lupus Erythematosus (SLE), are associated with increased incidence of hematological malignancies. The matricellular protein osteopontin (OPN) has been linked to SLE pathogenesis, as SLE patients show increased serum levels of OPN and often polymor...

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Detalles Bibliográficos
Autores principales: Rizzello, Celeste, Cancila, Valeria, Sangaletti, Sabina, Botti, Laura, Ratti, Chiara, Milani, Matteo, Dugo, Matteo, Bertoni, Francesco, Tripodo, Claudio, Chiodoni, Claudia, Colombo, Mario P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743519/
https://www.ncbi.nlm.nih.gov/pubmed/36503430
http://dx.doi.org/10.1186/s12943-022-01687-6

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