LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB

BACKGROUND: Alzheimer’s disease (AD) is the most common neurodegenerative disease worldwide but has no effective treatment. Amyloid beta (Aβ) protein, a primary risk factor for AD, accumulates and aggregates in the brain of patients with AD. Paired immunoglobulin-like receptor B (PirB) has been iden...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Yuki, Matsubayashi, Junpei, Kawakami, Yutaka, Nishida, Ryohei, Kurihara, Yuji, Takei, Kohtaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743548/
https://www.ncbi.nlm.nih.gov/pubmed/36510132
http://dx.doi.org/10.1186/s10020-022-00581-7

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