Upregulated complement receptors correlate with Fc gamma receptor 3A-positive natural killer and natural killer-T cells in neuromyelitis optica spectrum disorder

BACKGROUND AND OBJECTIVES: Inhibition of terminal complement in neuromyelitis optica spectrum disorder (NMOSD) using eculizumab helps prevent relapses, but the exact mechanism of action of the drug remains unclear. Similarly, genetic variants in the Fc Gamma receptor 3A (FCGR3A), also known as CD16,...

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Detalles Bibliográficos
Autores principales: Nishiyama, Shuhei, Wright, Amy E., Lotan, Itay, Mikami, Takahisa, Paul, Friedemann, Aoki, Masashi, Levy, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743562/
https://www.ncbi.nlm.nih.gov/pubmed/36503481
http://dx.doi.org/10.1186/s12974-022-02661-1

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