Cargando…

The prognostic value of retinol binding protein in geriatric hip fractures after surgeries: A propensity score matching and 1-year follow-up study

BACKGROUND: We aimed to explore the predictive value of retinol binding protein (RBP) for outcomes of hip fractures. METHODS: Patients with hip fractures who underwent hip surgeries between December 2017 and February 2021 and met the inclusion criteria were analyzed. Propensity score matching was us...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Mingchong, Yang, Chensong, Xu, Xian, Ji, Shengchao, Pan, Yutao, Han, Ning, Chang, Shimin, Sun, Guixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743574/
https://www.ncbi.nlm.nih.gov/pubmed/36510169
http://dx.doi.org/10.1186/s12891-022-06068-0
_version_ 1784848751832072192
author Liu, Mingchong
Yang, Chensong
Xu, Xian
Ji, Shengchao
Pan, Yutao
Han, Ning
Chang, Shimin
Sun, Guixin
author_facet Liu, Mingchong
Yang, Chensong
Xu, Xian
Ji, Shengchao
Pan, Yutao
Han, Ning
Chang, Shimin
Sun, Guixin
author_sort Liu, Mingchong
collection PubMed
description BACKGROUND: We aimed to explore the predictive value of retinol binding protein (RBP) for outcomes of hip fractures. METHODS: Patients with hip fractures who underwent hip surgeries between December 2017 and February 2021 and met the inclusion criteria were analyzed. Propensity score matching was used to reduce the bias of co-factors and ROC curves based on matched populations were created to determine the optimal cutoff point of RBP. The outcomes between patients with low levels of RBP and high levels of RBP were compared. RESULTS: Four hundred eighty patients were enrolled in this study and 69 patients died within one year. After a 1:1 PSM, patients with more than 1-year survival had significantly higher RBP (p = 0.013) than those who died within one year, as well as patients divided by 6-months survival (p = 0.012). Logistics analysis showed that low RBP may be an independent risk factor for 3-month survival, 6-month survival, 1-year survival, and 3-month free walking ability. CONCLUSION: RBP may be associated with the survival and 3-month walking abilities of patients with hip fractures.
format Online
Article
Text
id pubmed-9743574
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-97435742022-12-13 The prognostic value of retinol binding protein in geriatric hip fractures after surgeries: A propensity score matching and 1-year follow-up study Liu, Mingchong Yang, Chensong Xu, Xian Ji, Shengchao Pan, Yutao Han, Ning Chang, Shimin Sun, Guixin BMC Musculoskelet Disord Research BACKGROUND: We aimed to explore the predictive value of retinol binding protein (RBP) for outcomes of hip fractures. METHODS: Patients with hip fractures who underwent hip surgeries between December 2017 and February 2021 and met the inclusion criteria were analyzed. Propensity score matching was used to reduce the bias of co-factors and ROC curves based on matched populations were created to determine the optimal cutoff point of RBP. The outcomes between patients with low levels of RBP and high levels of RBP were compared. RESULTS: Four hundred eighty patients were enrolled in this study and 69 patients died within one year. After a 1:1 PSM, patients with more than 1-year survival had significantly higher RBP (p = 0.013) than those who died within one year, as well as patients divided by 6-months survival (p = 0.012). Logistics analysis showed that low RBP may be an independent risk factor for 3-month survival, 6-month survival, 1-year survival, and 3-month free walking ability. CONCLUSION: RBP may be associated with the survival and 3-month walking abilities of patients with hip fractures. BioMed Central 2022-12-12 /pmc/articles/PMC9743574/ /pubmed/36510169 http://dx.doi.org/10.1186/s12891-022-06068-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Liu, Mingchong
Yang, Chensong
Xu, Xian
Ji, Shengchao
Pan, Yutao
Han, Ning
Chang, Shimin
Sun, Guixin
The prognostic value of retinol binding protein in geriatric hip fractures after surgeries: A propensity score matching and 1-year follow-up study
title The prognostic value of retinol binding protein in geriatric hip fractures after surgeries: A propensity score matching and 1-year follow-up study
title_full The prognostic value of retinol binding protein in geriatric hip fractures after surgeries: A propensity score matching and 1-year follow-up study
title_fullStr The prognostic value of retinol binding protein in geriatric hip fractures after surgeries: A propensity score matching and 1-year follow-up study
title_full_unstemmed The prognostic value of retinol binding protein in geriatric hip fractures after surgeries: A propensity score matching and 1-year follow-up study
title_short The prognostic value of retinol binding protein in geriatric hip fractures after surgeries: A propensity score matching and 1-year follow-up study
title_sort prognostic value of retinol binding protein in geriatric hip fractures after surgeries: a propensity score matching and 1-year follow-up study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743574/
https://www.ncbi.nlm.nih.gov/pubmed/36510169
http://dx.doi.org/10.1186/s12891-022-06068-0
work_keys_str_mv AT liumingchong theprognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT yangchensong theprognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT xuxian theprognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT jishengchao theprognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT panyutao theprognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT hanning theprognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT changshimin theprognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT sunguixin theprognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT liumingchong prognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT yangchensong prognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT xuxian prognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT jishengchao prognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT panyutao prognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT hanning prognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT changshimin prognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy
AT sunguixin prognosticvalueofretinolbindingproteiningeriatrichipfracturesaftersurgeriesapropensityscorematchingand1yearfollowupstudy