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OR2AT4 and OR1A2 counterregulate molecular pathophysiological processes of steroid-resistant inflammatory lung diseases in human alveolar macrophages
BACKGROUND: Therapeutic options for steroid-resistant non-type 2 inflammation in obstructive lung diseases are lacking. Alveolar macrophages are central in the progression of these diseases by releasing proinflammatory cytokines, making them promising targets for new therapeutic approaches. Extra na...
Autores principales: | Weidinger, Daniel, Jamal Jameel, Kaschin, Alisch, Desiree, Jacobsen, Julian, Bürger, Paul, Ruhe, Matthias, Yusuf, Faisal, Rohde, Simon, Störtkuhl, Klemens, Kaufmann, Peter, Kronsbein, Juliane, Peters, Marcus, Hatt, Hanns, Giannakis, Nikolaos, Knobloch, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743598/ https://www.ncbi.nlm.nih.gov/pubmed/36503361 http://dx.doi.org/10.1186/s10020-022-00572-8 |
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