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OR2AT4 and OR1A2 counterregulate molecular pathophysiological processes of steroid-resistant inflammatory lung diseases in human alveolar macrophages

BACKGROUND: Therapeutic options for steroid-resistant non-type 2 inflammation in obstructive lung diseases are lacking. Alveolar macrophages are central in the progression of these diseases by releasing proinflammatory cytokines, making them promising targets for new therapeutic approaches. Extra na...

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Detalles Bibliográficos
Autores principales: Weidinger, Daniel, Jamal Jameel, Kaschin, Alisch, Desiree, Jacobsen, Julian, Bürger, Paul, Ruhe, Matthias, Yusuf, Faisal, Rohde, Simon, Störtkuhl, Klemens, Kaufmann, Peter, Kronsbein, Juliane, Peters, Marcus, Hatt, Hanns, Giannakis, Nikolaos, Knobloch, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743598/
https://www.ncbi.nlm.nih.gov/pubmed/36503361
http://dx.doi.org/10.1186/s10020-022-00572-8

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