Application of Box-Behnken experimental design and response surface methodology for selecting the optimum RP-HPLC conditions for the simultaneous determination of methocarbamol, indomethacin and betamethasone in their pharmaceutical dosage form

An isocratic RP-HPLC method has been developed for the separation and determination of methocarbamol (MTL), indomethacin (IND), and betamethasone (BET) in combined dosage form using an Inertsil ODS-3v C18 (250 × 4.6 mm, 5 μm) column with UV- detection at 235 nm. Experimental design using Box-Behnken...

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Detalles Bibliográficos
Autores principales: Elkady, Ehab F., Fouad, Marwa A., Mozayad, Ayoub N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743662/
https://www.ncbi.nlm.nih.gov/pubmed/36510282
http://dx.doi.org/10.1186/s13065-022-00908-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743662/
https://www.ncbi.nlm.nih.gov/pubmed/36510282
http://dx.doi.org/10.1186/s13065-022-00908-9

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