Bilateral mydriasis as first manifestation of Hodgkin’s lymphoma: a case report

BACKGROUND: Bilateral mydriasis is usually associated with severe brain stem damage or drug-induced sympathomimetic stimulation. Herein we report it as a unique neurologic complication of Hodgkin’s lymphoma. CASE PRESENTATION: A 23-year-old woman presented at our emergency department with dilated pu...

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Autores principales: Baki, Enayatullah, Scheidhauer, Klemens, Schmidt-Graf, Friederike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743757/
https://www.ncbi.nlm.nih.gov/pubmed/36503418
http://dx.doi.org/10.1186/s12883-022-02941-6
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author Baki, Enayatullah
Scheidhauer, Klemens
Schmidt-Graf, Friederike
author_facet Baki, Enayatullah
Scheidhauer, Klemens
Schmidt-Graf, Friederike
author_sort Baki, Enayatullah
collection PubMed
description BACKGROUND: Bilateral mydriasis is usually associated with severe brain stem damage or drug-induced sympathomimetic stimulation. Herein we report it as a unique neurologic complication of Hodgkin’s lymphoma. CASE PRESENTATION: A 23-year-old woman presented at our emergency department with dilated pupils unresponsive to light stimuli. MRI and CT scans showed bilaterally enlarged lymph nodes in the mediastinum and supraclavicular compressing the carotid artery on both sides. The histologic examination of lymph node biopsy specimens confirmed the diagnosis of Hodgkin’s lymphoma. CONCLUSION: Pathologies around the carotid artery causing oculosympathetic spasm should be considered among the possible causes of a mydriasis, especially when other common causes like brain stem impairment are excluded.
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spelling pubmed-97437572022-12-13 Bilateral mydriasis as first manifestation of Hodgkin’s lymphoma: a case report Baki, Enayatullah Scheidhauer, Klemens Schmidt-Graf, Friederike BMC Neurol Case Report BACKGROUND: Bilateral mydriasis is usually associated with severe brain stem damage or drug-induced sympathomimetic stimulation. Herein we report it as a unique neurologic complication of Hodgkin’s lymphoma. CASE PRESENTATION: A 23-year-old woman presented at our emergency department with dilated pupils unresponsive to light stimuli. MRI and CT scans showed bilaterally enlarged lymph nodes in the mediastinum and supraclavicular compressing the carotid artery on both sides. The histologic examination of lymph node biopsy specimens confirmed the diagnosis of Hodgkin’s lymphoma. CONCLUSION: Pathologies around the carotid artery causing oculosympathetic spasm should be considered among the possible causes of a mydriasis, especially when other common causes like brain stem impairment are excluded. BioMed Central 2022-12-12 /pmc/articles/PMC9743757/ /pubmed/36503418 http://dx.doi.org/10.1186/s12883-022-02941-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Baki, Enayatullah
Scheidhauer, Klemens
Schmidt-Graf, Friederike
Bilateral mydriasis as first manifestation of Hodgkin’s lymphoma: a case report
title Bilateral mydriasis as first manifestation of Hodgkin’s lymphoma: a case report
title_full Bilateral mydriasis as first manifestation of Hodgkin’s lymphoma: a case report
title_fullStr Bilateral mydriasis as first manifestation of Hodgkin’s lymphoma: a case report
title_full_unstemmed Bilateral mydriasis as first manifestation of Hodgkin’s lymphoma: a case report
title_short Bilateral mydriasis as first manifestation of Hodgkin’s lymphoma: a case report
title_sort bilateral mydriasis as first manifestation of hodgkin’s lymphoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743757/
https://www.ncbi.nlm.nih.gov/pubmed/36503418
http://dx.doi.org/10.1186/s12883-022-02941-6
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