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HSPB5 suppresses renal inflammation and protects lupus-prone NZB/W F1 mice from severe renal damage

BACKGROUND: Lupus nephritis (LN) is an inflammatory disease of the kidneys affecting patients with systemic lupus erythematosus. Current immunosuppressive and cytotoxic therapies are associated with serious side effects and fail to protect 20–40% of LN patients from end-stage renal disease. In this...

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Detalles Bibliográficos
Autores principales: Knapp, Justin, Braunstein, Marsela, Berg, Spencer Iner Thomas, Shirriff, Cody
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743758/
https://www.ncbi.nlm.nih.gov/pubmed/36510250
http://dx.doi.org/10.1186/s13075-022-02958-9

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