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HSPB5 suppresses renal inflammation and protects lupus-prone NZB/W F1 mice from severe renal damage
BACKGROUND: Lupus nephritis (LN) is an inflammatory disease of the kidneys affecting patients with systemic lupus erythematosus. Current immunosuppressive and cytotoxic therapies are associated with serious side effects and fail to protect 20–40% of LN patients from end-stage renal disease. In this...
Autores principales: | Knapp, Justin, Braunstein, Marsela, Berg, Spencer Iner Thomas, Shirriff, Cody |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743758/ https://www.ncbi.nlm.nih.gov/pubmed/36510250 http://dx.doi.org/10.1186/s13075-022-02958-9 |
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