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Surrogate endpoints in trials: a call for better reporting

Using a surrogate endpoint as a substitute for a patient-relevant final outcome enables randomised controlled trials (RCTs) to be conducted more efficiently. However, the use of surrogates remains controversial and there is currently no guideline for the reporting of RCTs using surrogate endpoints;...

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Detalles Bibliográficos
Autores principales: Ciani, Oriana, Manyara, Anthony M., Chan, An-Wen, Taylor, Rod S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743760/
https://www.ncbi.nlm.nih.gov/pubmed/36503559
http://dx.doi.org/10.1186/s13063-022-06904-7