Cargando…

Molecular pathways, resistance mechanisms and targeted interventions in non-small-cell lung cancer

Lung cancer is the leading cause of cancer-related mortality worldwide. The discovery of tyrosine kinase inhibitors effectively targeting EGFR mutations in lung cancer patients in 2004 represented the beginning of the precision medicine era for this refractory disease. This great progress benefits f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zixi, Xing, Yurou, Li, Bingjie, Li, Xiaoyu, Liu, Bin, Wang, Yongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Nature Singapore 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743956/ https://www.ncbi.nlm.nih.gov/pubmed/36508072 http://dx.doi.org/10.1186/s43556-022-00107-x

Ejemplares similares

Advances in Targeted Therapy and Immunotherapy for Non-small Cell Lung Cancer Based on Accurate Molecular Typing
por: Dong, Jingsi, et al.
Publicado: (2019)

Radiotherapy combined with immunotherapy successfully treated one case of anaplastic thyroid cancer: A case report
por: Xing, Yurou, et al.
Publicado: (2023)

Curcumin: Updated Molecular Mechanisms and Intervention Targets in Human Lung Cancer
por: Ye, Ming-Xiang, et al.
Publicado: (2012)

Molecular Mechanisms Contributing to Resistance to Tyrosine Kinase-Targeted Therapy for Non-Small Cell Lung Cancer
por: Nurwidya, Fariz, et al.
Publicado: (2012)

Non-small-cell lung cancer: molecular targeted therapy and personalized medicine – drug resistance, mechanisms, and strategies
por: Sechler, Marybeth, et al.
Publicado: (2013)

Signaling pathways in macrophages: molecular mechanisms and therapeutic targets
por: Li, Ming, et al.
Publicado: (2023)

Acquired resistance to osimertinib in patients with non-small-cell lung cancer: mechanisms and clinical outcomes
por: Mu, Yuxin, et al.
Publicado: (2020)

Partial treatment response to alectinib in metastatic non-small cell lung cancer with KIDINS220-ALK fusion
por: Lei, Yanna, et al.
Publicado: (2023)

Inflammation and tumor progression: signaling pathways and targeted intervention
por: Zhao, Huakan, et al.
Publicado: (2021)

Signaling pathways in vascular function and hypertension: molecular mechanisms and therapeutic interventions
por: Ma, Jun, et al.
Publicado: (2023)

Sarcopenia: Molecular Pathways and Potential Targets for Intervention
por: Pascual-Fernández, Jorge, et al.
Publicado: (2020)

Novel Targets and Small Molecular Interventions for Liver Cancer
por: Jiang, Chunping, et al.
Publicado: (2014)

Non-Small Cell Lung Cancer Targeted Therapy: Drugs and Mechanisms of Drug Resistance
por: Wu, Jiajia, et al.
Publicado: (2022)

Signaling pathways in Parkinson’s disease: molecular mechanisms and therapeutic interventions
por: Dong-Chen, Xu, et al.
Publicado: (2023)

Advances in molecular-based personalized non-small-cell lung cancer therapy: targeting epidermal growth factor receptor and mechanisms of resistance
por: Jotte, Robert M, et al.
Publicado: (2015)

Novel mechanism of resistance to targeted therapies in lung cancer
por: Wang, Walter, et al.
Publicado: (2018)

Dynamic Network of Transcription and Pathway Crosstalk to Reveal Molecular Mechanism of MGd-Treated Human Lung Cancer Cells
por: Shao, Liyan, et al.
Publicado: (2012)

Molecular pathways and therapeutic targets in lung cancer
por: Shtivelman, Emma, et al.
Publicado: (2014)

Is lobectomy superior to sub-lobectomy in non-small cell lung cancer with pleural invasion? A population-based competing risk analysis
por: Song, Xue, et al.
Publicado: (2022)

The potential of high-order features of routine blood test in predicting the prognosis of non-small cell lung cancer
por: Luo, Liping, et al.
Publicado: (2023)

FAT10 is associated with the malignancy and drug resistance of non-small-cell lung cancer
por: Xue, Feng, et al.
Publicado: (2016)

Continuous targeted kinase inhibitors treatment induces upregulation of PD-L1 in resistant NSCLC
por: Jiang, Li, et al.
Publicado: (2019)

Mechanisms of Acquired Resistance and Tolerance to EGFR Targeted Therapy in Non-Small Cell Lung Cancer
por: Chhouri, Houssein, et al.
Publicado: (2023)

Berberine induces non-small cell lung cancer apoptosis via the activation of the ROS/ASK1/JNK pathway
por: Chen, Qianqian, et al.
Publicado: (2022)

Targeting HDAC with a novel inhibitor effectively reverses paclitaxel resistance in non-small cell lung cancer via multiple mechanisms
por: Wang, L, et al.
Publicado: (2016)

Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions
por: Qin, Chuan, et al.
Publicado: (2022)

The action mechanism of lncRNA-HOTAIR on the drug resistance of non-small cell lung cancer by regulating Wnt signaling pathway
por: Guo, Feng, et al.
Publicado: (2018)

Development of dual-targeted nano-dandelion based on an oligomeric hyaluronic acid polymer targeting tumor-associated macrophages for combination therapy of non-small cell lung cancer
por: Wang, Bingjie, et al.
Publicado: (2019)

Targeted Immunotherapies in Gastrointestinal Cancer: From Molecular Mechanisms to Implications
por: Wang, Ding-Kang, et al.
Publicado: (2021)

MiR‐630 suppresses non‐small cell lung cancer by targeting vimentin
por: Wang, Bin, et al.
Publicado: (2022)

Molecular Characteristics of Rifampin-Sensitive and -Resistant Isolates and Characteristics of rpoB Gene Mutations in Methicillin-Resistant Staphylococcus aureus
por: Guo, Yinjuan, et al.
Publicado: (2021)

Preparation and Application of Molecularly Imprinted Polymers for Flavonoids: Review and Perspective
por: Yang, Yurou, et al.
Publicado: (2022)

A Novel Systems Pharmacology Method to Investigate Molecular Mechanisms of Scutellaria barbata D. Don for Non-small Cell Lung Cancer
por: Liu, Jianling, et al.
Publicado: (2018)

Integrated bioinformatics and network pharmacology to explore the therapeutic target and molecular mechanisms of Taxus chinensis against non-small cell lung cancer
por: Zhang, Shujuan, et al.
Publicado: (2023)

Molecular Mechanisms in Genetic Aortopathy–Signaling Pathways and Potential Interventions
por: Dong, Charlotte Xue, et al.
Publicado: (2023)

Drug Resistance to Molecular Targeted Therapy and Its Consequences for Treatment Decisions in Non-Small-Cell Lung Cancer
por: Spaans, Johanna N., et al.
Publicado: (2014)

Molecular mechanisms of platinum-based chemotherapy resistance in ovarian cancer
por: Yang, Ling, et al.
Publicado: (2022)

The Inhibitory Mechanism of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as Inhibitors of P21-Activated Kinase 4 through Molecular Dynamics Simulation
por: Du, Juan, et al.
Publicado: (2023)

Drug Resistance Mechanisms in Non-Small Cell Lung Carcinoma
por: Wangari-Talbot, Janet, et al.
Publicado: (2013)

Baicalin Relieves LPS-Induced Lung Inflammation via the NF-κB and MAPK Pathways
por: Shen, Bingyu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hkt807p0gfgvbfof63c5baqu7e