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M(6)A RNA Methylation-Based Epitranscriptomic Modifications in Plasticity-Related Genes via miR-124-C/EBPα-FTO-Transcriptional Axis in the Hippocampus of Learned Helplessness Rats

BACKGROUND: Impaired synaptic plasticity has been linked to dynamic gene regulatory network changes. Recently, gene regulation has been introduced with the emerging concept of unique N6-methyladenosine (m(6)A)-based reversible transcript methylation. In this study, we tested whether m(6)A RNA methyl...

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Detalles Bibliográficos
Autores principales: Roy, Bhaskar, Ochi, Shinichiro, Dwivedi, Yogesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9743968/
https://www.ncbi.nlm.nih.gov/pubmed/36161325
http://dx.doi.org/10.1093/ijnp/pyac068

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