Cargando…
Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles
Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744106/ https://www.ncbi.nlm.nih.gov/pubmed/36544466 http://dx.doi.org/10.1039/d2ra06306a |
_version_ | 1784848848492953600 |
---|---|
author | Colombo, Eleonora Coppini, Davide Andrea Maculan, Simone Seneci, Pierfausto Santini, Benedetta Testa, Filippo Salvioni, Lucia Vanacore, Giovanni Maria Colombo, Miriam Passarella, Daniele |
author_facet | Colombo, Eleonora Coppini, Davide Andrea Maculan, Simone Seneci, Pierfausto Santini, Benedetta Testa, Filippo Salvioni, Lucia Vanacore, Giovanni Maria Colombo, Miriam Passarella, Daniele |
author_sort | Colombo, Eleonora |
collection | PubMed |
description | Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined. |
format | Online Article Text |
id | pubmed-9744106 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-97441062022-12-20 Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles Colombo, Eleonora Coppini, Davide Andrea Maculan, Simone Seneci, Pierfausto Santini, Benedetta Testa, Filippo Salvioni, Lucia Vanacore, Giovanni Maria Colombo, Miriam Passarella, Daniele RSC Adv Chemistry Hetero-nanoparticles self-assembled from a conjugate bearing folic acid as the targeting agent, and another bearing paclitaxel as the active agent are reported. Hetero-nanoparticles containing varying percentages of folic acid conjugates are characterised, and their biological activity is determined. The Royal Society of Chemistry 2022-12-12 /pmc/articles/PMC9744106/ /pubmed/36544466 http://dx.doi.org/10.1039/d2ra06306a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/ |
spellingShingle | Chemistry Colombo, Eleonora Coppini, Davide Andrea Maculan, Simone Seneci, Pierfausto Santini, Benedetta Testa, Filippo Salvioni, Lucia Vanacore, Giovanni Maria Colombo, Miriam Passarella, Daniele Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles |
title | Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles |
title_full | Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles |
title_fullStr | Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles |
title_full_unstemmed | Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles |
title_short | Folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles |
title_sort | folic acid functionalization for targeting self-assembled paclitaxel-based nanoparticles |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744106/ https://www.ncbi.nlm.nih.gov/pubmed/36544466 http://dx.doi.org/10.1039/d2ra06306a |
work_keys_str_mv | AT colomboeleonora folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles AT coppinidavideandrea folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles AT maculansimone folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles AT senecipierfausto folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles AT santinibenedetta folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles AT testafilippo folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles AT salvionilucia folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles AT vanacoregiovannimaria folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles AT colombomiriam folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles AT passarelladaniele folicacidfunctionalizationfortargetingselfassembledpaclitaxelbasednanoparticles |