Cargando…

Downregulated miRNA-491-3p accelerates colorectal cancer growth by increasing uMtCK expression

Colorectal carcinoma (CRC) is the second most frequent cancer worldwide. MiR-491-3p, a tumor-suppressive microRNA (miRNA, miR), has been revealed to be abnormally expressed in CRC tissues. Meanwhile, up-regulated ubiquitous mitochondrial creatine kinase (uMtCK) contributes to CRC cell proliferation....

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Xingkui, Lin, Yukun, He, Jialin, Luo, Xijun, Liang, Junjie, Zhu, Xianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744150/ https://www.ncbi.nlm.nih.gov/pubmed/36518289 http://dx.doi.org/10.7717/peerj.14285

Ejemplares similares

MiR-519b-3p Inhibits the Proliferation and Invasion in Colorectal Cancer via Modulating the uMtCK/Wnt Signaling Pathway
por: Zhang, Yuexiang, et al.
Publicado: (2019)

Retraction: MiR-519b-3p inhibits the proliferation and invasion in colorectal cancer via modulating the uMtCK/Wnt signaling pathway
Publicado: (2023)

Establishment and validation of a prognostic model based on HRR-related lncRNAs in colon adenocarcinoma
por: Tang, Xingkui, et al.
Publicado: (2022)

Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter
por: Uchida, Akira, et al.
Publicado: (2017)

Ischemic postconditioning influences electron transport chain protein turnover in Langendorff-perfused rat hearts
por: Cao, Song, et al.
Publicado: (2016)

Chondroitin sulfate E downregulates N-cadherin and suppresses myotube formation
por: SATOH, Fumi, et al.
Publicado: (2022)

Comprehensive miRNA expression profiles in the ilea of Lawsonia intracellularis-infected pigs
por: LI, Hongyi, et al.
Publicado: (2016)

Neuromedin U and neurotensin may promote the development of the tumour microenvironment in neuroblastoma
por: Yang, Daheng, et al.
Publicado: (2021)

CK1/Doubletime activity delays transcription activation in the circadian clock
por: Top, Deniz, et al.
Publicado: (2018)

Downregulation of the enhancer of zeste homolog 1 transcriptional factor predicts poor prognosis of triple-negative breast cancer patients
por: Peng, Wei, et al.
Publicado: (2022)

Analysis of conserved miRNAs in cynomolgus macaque genome using small RNA sequencing and homology searching
por: Huang, Xia, et al.
Publicado: (2020)

SorLA and CLC:CLF-1-dependent Downregulation of CNTFRα as Demonstrated by Western Blotting, Inhibition of Lysosomal Enzymes, and Immunocytochemistry
por: Larsen, Jakob V., et al.
Publicado: (2017)

Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA
por: Younis, Ihab, et al.
Publicado: (2013)

Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection
por: Lu, Feiran, et al.
Publicado: (2015)

ET-1 receptor type B (ETBR) overexpression associated with ICAM-1 downregulation leads to inflammatory attenuation in experimental autoimmune myocarditis
por: Yang, Peng, et al.
Publicado: (2023)

Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury
por: Tang, Wei, et al.
Publicado: (2021)

Rolling circle amplification (RCA) -based biosensor system for the fluorescent detection of miR-129-2-3p miRNA
por: Ye, Yan, et al.
Publicado: (2022)

The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction
por: Fourmann, Jean-Baptiste, et al.
Publicado: (2016)

Proteomic indicators of oxidation and hydration state in colorectal cancer
por: Dick, Jeffrey M.
Publicado: (2016)

RBiomirGS: an all-in-one miRNA gene set analysis solution featuring target mRNA mapping and expression profile integration
por: Zhang, Jing, et al.
Publicado: (2018)

Identification of key biomarkers based on the proliferation of secondary hyperparathyroidism by bioinformatics analysis and machine learning
por: Shen, Aiwen, et al.
Publicado: (2023)

Loss of Farnesoid X receptor (FXR) accelerates dysregulated glucose and renal injury in db/db mice
por: Qiu, Yuxiang, et al.
Publicado: (2023)

Transcription analyses of differentially expressed mRNAs, lncRNAs, circRNAs, and miRNAs in the growth plate of rats with glucocorticoid-induced growth retardation
por: Yin, Mingyue, et al.
Publicado: (2023)

Interface between 40S exit channel protein uS7/Rps5 and eIF2α modulates start codon recognition in vivo
por: Visweswaraiah, Jyothsna, et al.
Publicado: (2017)

Regulation of signal transduction pathways in colorectal cancer: implications for therapeutic resistance
por: Yeoh, Yeelon, et al.
Publicado: (2021)

Differential expression of skeletal muscle mitochondrial proteins in yak, dzo, and cattle: a proteomics-based study
por: LONG, Ling, et al.
Publicado: (2020)

TNFRSF10C methylation is a new epigenetic biomarker for colorectal cancer
por: Zhou, Cong, et al.
Publicado: (2018)

Accelerated construction of an in vitro model of human periodontal ligament tissue: vacuum plasma combined with fibronectin coating and a polydimethylsiloxane matrix
por: Liao, Wen, et al.
Publicado: (2019)

Identification of 10 Hub genes related to the progression of colorectal cancer by co-expression analysis
por: Meng, Jie, et al.
Publicado: (2020)

High cytoplasmic YAP1 expression predicts a poor prognosis in patients with colorectal cancer
por: Dong, Tianqi, et al.
Publicado: (2020)

SIX4 promotes metastasis via activation of the PI3K-AKT pathway in colorectal cancer
por: Li, Guodong, et al.
Publicado: (2017)

A model of multiple tumor marker for lymph node metastasis assessment in colorectal cancer: a retrospective study
por: Fu, Jiangping, et al.
Publicado: (2022)

The β-carboline alkaloid harmine inhibits telomerase activity of MCF-7 cells by down-regulating hTERT mRNA expression accompanied by an accelerated senescent phenotype
por: Zhao, Lei, et al.
Publicado: (2013)

Advanced oxidation protein products induce annulus fibrosus cell senescence through a NOX4-dependent, MAPK-mediated pathway and accelerate intervertebral disc degeneration
por: Dai, Xiangheng, et al.
Publicado: (2022)

Downregulation of miR‐491‐5p promotes gastric cancer metastasis by regulating SNAIL and FGFR4
por: Yu, Ting, et al.
Publicado: (2018)

miR-491-3p is Downregulated in Retinoblastoma and Inhibit Tumor Cells Growth and Metastasis by Targeting SNN
por: Hu, Yang, et al.
Publicado: (2020)

Cellular prion protein and γ-synuclein overexpression in LS 174T colorectal cancer cell drives endothelial proliferation-to-differentiation switch
por: Ong, Sing-Hui, et al.
Publicado: (2018)

Quantitative proteomics reveal proteins enriched in tubular endoplasmic reticulum of Saccharomyces cerevisiae
por: Wang, Xinbo, et al.
Publicado: (2017)

m(6)A reader IGF2BP1 accelerates apoptosis of high glucose-induced vascular endothelial cells in a m(6)A-HMGB1 dependent manner
por: Liang, Anru, et al.
Publicado: (2023)

SUN-491 An Uncommon Presentation of Primary Hiperparathyroidism
por: Bastos, Filipa, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7f830vsjqcpnjmt1q1a97i8pgv