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M1 macrophage-derived extracellular vesicle containing tsRNA-5006c promotes osteogenic differentiation of aortic valve interstitial cells through regulating mitophagy

BACKGROUND: Osteogenic differentiation of aortic valve interstitial cells (AVICs) plays a key role in the calcific aortic valve disease progression. Extracellular vesicles (EVs)-derived from M1-polarized macrophages (M1-EVs) orchestrated intercellular communication by delivering non-coding RNAs such...

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Detalles Bibliográficos
Autores principales:	Xia, Hao, Gao, Mingjian, Chen, Jun, Huang, Guanshen, Xiang, Xiuting, Wang, Yuyan, Huang, Zhaohui, Li, Yongchun, Su, Shuang, Zhao, Zewei, Zeng, Qingchun, Ruan, Yunjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744173/ https://www.ncbi.nlm.nih.gov/pubmed/36518291 http://dx.doi.org/10.7717/peerj.14307

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